Fludarabine and Cyclophosphamide Based Conditioning Is Associated with Good Outcomes in Patients Undergoing Matched Sibling Donor Transplants for Aplastic Anaemia
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DOI: 10.1182/blood-2019-129328
Abstract: Background: Fludarabine based conditioning protocols are increasingly being used for transplant (SCT) in patients with aplastic anaemia (AA) especially in those who have received multiple transfusions. Patients and Methods: Between January 2004 and June 2019,… read more here.
Keywords: fludarabine; patients undergoing; aplastic anaemia; based conditioning ... See more keywords
Total marrow irradiation based conditioning for allogeneic hematopoietic stem cell transplantation in elderly or frail patients with hematological malignancies: A single center analysis
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DOI: 10.1182/blood-2025-2444
Abstract: Background：Allogeneic hematopoietic stem-cell transplantation (allo-HSCT) remains the only potentially curative therapy for many hematological disorders, yet standard high-dose chemoradiation conditioning is associated with substantial toxicity-related mortality, especially in older adults or those with poor performance… read more here.
Keywords: marrow; irradiation; transplantation; based conditioning ... See more keywords
Comparison of alemtuzumab and ATG-based conditioning in adult recipients of allogeneic hematopoietic cell transplantation (HCT) for severe aplastic anemia: A retrospective study
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DOI: 10.1182/blood-2025-4207
Abstract: Background The optimal in-vivo T-cell depleting agent for allogeneic hematopoietic cell transplantation (HCT) for patients with severe aplastic anemia (SAA) remains unclear. Current guidelines endorse the use of either rabbit anti-thymocyte globulin (ATG) or alemtuzumab,… read more here.
Keywords: alemtuzumab atg; atg based; hct; cell ... See more keywords
Long-Term Outcomes of Treosulfan- vs. Busulfan-Based Conditioning Regimen for Patients With Myelodysplastic Syndrome and Acute Myeloid Leukemia Before Hematopoietic Cell Transplantation: A Systematic Review and Meta-Analysis
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DOI: 10.3389/fonc.2020.591363
Abstract: Background Many studies aimed to evaluate the efficacy and safety of treosulfan-based conditioning regimens for allogeneic hematopoietic cell transplantation (allo-HCT) compared with other regimens, but different outcomes were reported across studies. Aim To determine the… read more here.
Keywords: acute; treosulfan based; busulfan based; based conditioning ... See more keywords