Synthesis and Studies of Fluorescein Based Derivatives for their Optical Properties, Urease Inhibition and Molecular Docking
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Fluorescence"
DOI: 10.1007/s10895-018-2291-7
Abstract: Herein, we design and synthesized new fluorescein based derivatives by insitu formation of fluorescein ester and further treated with corresponding hydrazide and amine to yield respective compounds i.e. FB1, FB2, FB3 and FB4. The spectral… read more here.
Keywords: based derivatives; fluorescein based; inhibition; urease inhibition ... See more keywords
Anthracene-based derivatives: Synthesis, photophysical properties and electrochemical properties
Sign Up to like & getrecommendations! Published in 2017 at "Chemical Research in Chinese Universities"
DOI: 10.1007/s40242-017-6431-4
Abstract: A series of anthracene-based derivatives, namely, 9-(4-phenyl)anthracene(1), 9-(4-phenylethynyl)-anthracene(2) and 9, 10-bis(phenylethynyl)anthracene(3), was synthesized by the Suzuki/Sonogashira cross-coupling reactions in good yields. These compounds were fully characterized by X-ray crystallography, thermogravimetric analysis(TGA), differential scanning calorimetry(DSC), UV-Vis… read more here.
Keywords: based derivatives; electrochemical properties; synthesis photophysical; derivatives synthesis ... See more keywords
Visual sensing of formaldehyde via a solution-to-gel transition with cholesteryl naphthalimide-based derivatives
Sign Up to like & getrecommendations! Published in 2021 at "Dyes and Pigments"
DOI: 10.1016/j.dyepig.2021.109546
Abstract: Abstract It is relevant for individual and public health security to develop a simple protocol for visual sensing of formaldehyde (FA). Herein, two cholesteryl naphthalimide-based derivatives (1a and 1b) were developed to be FA chemosensors… read more here.
Keywords: cholesteryl naphthalimide; sensing formaldehyde; visual sensing; naphthalimide based ... See more keywords
Novel biguanide-based derivatives scouted as TAAR1 agonists: Synthesis, biological evaluation, ADME prediction and molecular docking studies.
Sign Up to like & getrecommendations! Published in 2017 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2016.10.058
Abstract: Trace amines (TAs) are endogenous neuromodulators that play a functional role in the synaptic transmission within central nervous system (CNS), targeting trace amine-associated receptors (TAARs). Starting from our previous computational studies on TAAR1 and TAAR5… read more here.
Keywords: based derivatives; murine; biguanide based; taar1 agonists ... See more keywords
Melem-based derivatives as metal-free photocatalysts for simultaneous reduction of Cr(VI) and degradation of 5-Sulfosalicylic acid.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of colloid and interface science"
DOI: 10.1016/j.jcis.2017.07.099
Abstract: Carbon nitride has been considered as promising metal-free polymers for low-cost photocatalysis. Most prevailing concern about this fantastic material focuses on g-C3N4, while the potential of other derivatives have been overlooked. Herein, in order to… read more here.
Keywords: based derivatives; photocatalysts simultaneous; melem based; derivatives metal ... See more keywords
Carbon-based derivatives from metal-organic frameworks as cathode hosts for Li–S batteries
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Energy Chemistry"
DOI: 10.1016/j.jechem.2019.01.005
Abstract: Abstract Lithium-sulfur batteries (Li–S batteries) are promising candidates for the next generation high-energy rechargeable Li batteries due to their high theoretical specific capacity (1672 mAh g−1) and energy density (2500 Wh kg−1). The commercialization of Li–S batteries… read more here.
Keywords: derivatives metal; organic frameworks; cathode hosts; carbon based ... See more keywords
Design, synthesis, biological evaluation, and molecular docking study on triazine based derivatives as anti-inflammatory agents
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2021.130760
Abstract: Abstract In an attempt to develop new anti-inflammatory agents, design, synthesis, pharmacological activities, and docking study of two groups of triazine-based derivatives were reported. Nine compounds (5a-5d and 10a-10e) consisting of triazine, vanillin, and phenylpyrazole… read more here.
Keywords: inflammatory agents; design synthesis; anti inflammatory; triazine based ... See more keywords
Design, Synthesis, Antifungal Evaluation, and Action Mechanism of Novel l-Carvone-Based Derivatives as Potential Succinate Dehydrogenase Inhibitors.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.4c10500
Abstract: Natural products serve as a crucial source of compounds for developing novel agricultural antifungals. In this work, we utilized the natural product l-carvone as a molecular scaffold to design and synthesize three series of novel… read more here.
Keywords: novel carvone; succinate dehydrogenase; carvone; mechanism ... See more keywords
Discovery of Novel Natural Maltol-Based Derivatives as Potential Succinate Dehydrogenase Inhibitors.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.5c09599
Abstract: To develop novel fungicidal agents, 40 novel maltol-based derivatives were designed, synthesized, and evaluated for antifungal activity. Most compounds exhibited potent in vitro efficacy against phytopathogenic fungi, with A2, A3, A4, A8, A9, A23, A24,… read more here.
Keywords: compound a24; succinate dehydrogenase; maltol based; based derivatives ... See more keywords
Novel Isoalantolactone-Based Derivatives as Potent NLRP3 Inflammasome Inhibitors: Design, Synthesis, and Biological Characterization.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.4c00357
Abstract: The NLRP3 inflammasome has been recognized as a promising therapeutic target in drug discovery for inflammatory diseases. Our initial research identified a natural sesquiterpene isoalantolactone (IAL) as the active scaffold targeting NLRP3 inflammasome. To improve… read more here.
Keywords: novel isoalantolactone; potent nlrp3; nlrp3 inflammasome; based derivatives ... See more keywords
Discovery of Novel Pyrimidine-Based Derivatives as Nav1.2 Inhibitors with Efficacy in Mouse Models of Epilepsy.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.4c00861
Abstract: Dysfunction of voltage-gated sodium channel Nav1.2 causes various epileptic disorders, and inhibition of the channel has emerged as an attractive therapeutic strategy. However, currently available Nav1.2 inhibitors exhibit low potency and limited structural diversity. In… read more here.
Keywords: nav1 inhibitors; pyrimidine based; based derivatives; discovery novel ... See more keywords