Recent Trends in Clinical Trials Related to Carrier-Based Drugs.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2017.02.026
Abstract: Clinical trials related to carrier-based drugs have recently attracted attention because carrier-based drugs hold promise for high efficiency drug delivery and for reducing drug-related side effects. In this commentary, we introduce recent clinical trials involving… read more here.
Keywords: trials related; carrier based; related carrier; clinical trials ... See more keywords
Substance P Mediated DGLs Complexing with DACHPt for Targeting Therapy of Glioma.
Sign Up to like & getrecommendations! Published in 2017 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.7b05997
Abstract: Currently, glioblastoma (glioma) is described as the deadliest brain tumor for its invasive natural with exceeding difficulty in surgical excision. Blood-brain barrier (BBB) can restrict the penetration of most therapeutic reagents including platinum (Pt)-based drugs-the… read more here.
Keywords: substance mediated; glioma; dachpt; mediated dgls ... See more keywords
Nanoparticle-Based Drugs and Formulations: Current Status and Emerging Applications
Sign Up to like & getrecommendations! Published in 2020 at "ACS Applied Nano Materials"
DOI: 10.1021/acsanm.0c00606
Abstract: In the foreseeable future, pharmaceuticals market, nanomedicine and healthcare system will largely depend on the drug nanoparticles formulation technology. Perceiving this, a significant amount of ... read more here.
Keywords: current status; nanoparticle based; formulations current; drugs formulations ... See more keywords
Comparative NMR metabolomics of the responses of A2780 human ovarian cancer cells to clinically established Pt-based drugs.
Sign Up to like & getrecommendations! Published in 2022 at "Dalton transactions"
DOI: 10.1039/d2dt02068h
Abstract: Pt-Based drugs play a very important role in current cancer treatments; yet, their cellular and mechanistic aspects are not fully understood. NMR metabolomics provides a powerful tool to investigate the metabolic perturbations induced by Pt… read more here.
Keywords: cancer; cancer cells; nmr metabolomics; responses a2780 ... See more keywords
Fibroblast growth factors in control of lipid metabolism: from biological function to clinical application
Sign Up to like & getrecommendations! Published in 2019 at "Current Opinion in Lipidology"
DOI: 10.1097/mol.0000000000000599
Abstract: Purpose of review Several members of the fibroblast growth factor (FGF) family have been identified as key regulators of energy metabolism in rodents and nonhuman primates. Translational studies show that their metabolic actions are largely… read more here.
Keywords: growth factors; fgf based; fibroblast growth; metabolism ... See more keywords
Prescribing cannabis based drugs: response from NICE and Health Education England
Sign Up to like & getrecommendations! Published in 2018 at "British Medical Journal"
DOI: 10.1136/bmj.k4940
Abstract: Further to Hamilton’s recommendation that general practitioners consult Google Scholar and ask their colleagues if they are unsure about prescribing cannabis,1 we write to remind readers in England that they have 24/7 access to reliable… read more here.
Keywords: cannabis based; evidence; drugs response; health ... See more keywords
Platinum-Based Drugs Differentially Affect the Ultrastructure of Breast Cancer Cell Types
Sign Up to like & getrecommendations! Published in 2017 at "BioMed Research International"
DOI: 10.1155/2017/3178794
Abstract: Breast cancer (BC) is the most common cause of cancer-related death worldwide. Although platinum-based drugs (PBDs) are effective anticancer agents, responsive patients eventually become resistant. While resistance of some cancers to PBDs has been explored,… read more here.
Keywords: platinum based; breast cancer; cancer; cell ... See more keywords
Natural Products-based Drugs: Potential Drug Targets Against Neurological Degeneration.
Sign Up to like & getrecommendations! Published in 2023 at "Current neuropharmacology"
DOI: 10.2174/1570159x21666230220102605
Abstract: Phytochemicals or natural products have been studied extensively for their potential in the treatment of neurodegenerative diseases (NDs) like Parkinson's disease, Alzheimer's disease, etc. The neuronal structure loss and progressive dysfunction are the main characteristics… read more here.
Keywords: potential drug; based drugs; natural products; drugs potential ... See more keywords
Spectroscopic Approaches to Tracking Metal-based Drugs in Cells and Tissue.
Sign Up to like & getrecommendations! Published in 2017 at "Chimia"
DOI: 10.2533/chimia.2017.112
Abstract: Metal-based drugs with novel targets and modes of action are increasingly being developed as alternatives to classical platinum(ii) chemotherapeutics. Imaging methods in tumour cells and tissues offer valuable insights into the behaviour of these novel… read more here.
Keywords: tracking metal; metal; spectroscopic approaches; metal based ... See more keywords
RNA-based drugs and regulation: Toward a necessary evolution of the definitions issued from the European union legislation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.1012497
Abstract: Many RNA-based drugs, both vaccines and non-vaccines, are under development or even approved. They include coding mRNAs and non-coding (nc) RNAs among them antisense oligonucleotides (ASOs), small interfering RNAs (siRNAs), micro-RNAs (miRNAs), small activating RNAs… read more here.
Keywords: union legislation; rna based; european union; based drugs ... See more keywords
Overcoming therapeutic resistance to platinum-based drugs by targeting Epithelial–Mesenchymal transition
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.1008027
Abstract: Platinum-based drugs (PBDs), including cisplatin, carboplatin, and oxaliplatin, have been widely used in clinical practice as mainstay treatments for various types of cancer. Although there is firm evidence of notable achievements with PBDs in the… read more here.
Keywords: mesenchymal transition; resistance; epithelial mesenchymal; based drugs ... See more keywords