Cystatin C-based eGFR better predicts renal vancomycin clearance than creatinine-based eGFR in patients with allogeneic stem cell transplantation.
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DOI: 10.1002/cpt.70125
Abstract: Knowledge of the glomerular filtration rate (GFR) is mandatory when dosing renally eliminated drugs such as vancomycin. In clinical practice, different biomarkers and various equations are used to estimate GFR (eGFR), resulting in varying estimates.… read more here.
Keywords: renal vancomycin; cystatin based; creatinine based; based egfr ... See more keywords
Creatinine-based estimated glomerular filtration rate for children younger than 2 years
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DOI: 10.1007/s10157-017-1460-3
Abstract: To the Editor Serum creatinine (Cr)-based eGFR may be used for Japanese children aged 2–18 years to evaluate renal function, measuring serum Cr by enzymatic method [1]. In clinical practice, cystatin C (cysC)-based eGFR [2]… read more here.
Keywords: estimated glomerular; younger years; creatinine based; children aged ... See more keywords
Macrocyclization of Quinazoline-Based EGFR Inhibitors Leads to Exclusive Mutant Selectivity for EGFR L858R and Del19.
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DOI: 10.1021/acs.jmedchem.2c01041
Abstract: Activating mutations in the epidermal growth factor receptor (EGFR) are frequent oncogenic drivers of non-small-cell lung cancer (NSCLC). The most frequent alterations in EGFR are short in-frame deletions in exon 19 (Del19) and the missense… read more here.
Keywords: macrocyclization quinazoline; based egfr; egfr inhibitors; quinazoline ... See more keywords
Association of Intraindividual Difference in Cystatin C and Creatinine Estimated Glomerular Filtration Rate With Diabetes
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DOI: 10.1155/jdr/9335243
Abstract: Introduction Declined renal function is closely linked to diabetes. However, it remains unclear whether the intraindividual difference between cystatin C- and creatinine-based estimated glomerular filtration rates (eGFRdiff) is associated with diabetes. This study was aimed… read more here.
Keywords: difference cystatin; creatinine based; based egfr; cystatin creatinine ... See more keywords