Discovery and Characterization of a Novel Chitosanase from Paenibacillus dendritiformis by Phylogeny-Based Enzymatic Product Specificity Prediction.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.7b06067
Abstract: In the process of genome mining for novel chitosanases by phylogeny-based enzymatic product specificity prediction, a gene named Csn-PD from Paenibacillus dendritiformis was discovered. The enzyme was classified as a member of the GH46 family… read more here.
Keywords: phylogeny based; product specificity; product; enzymatic product ... See more keywords
Synthesis of new hydrophilic rhodamine based enzymatic substrates compatible with droplet-based microfluidic assays.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical communications"
DOI: 10.1039/c7cc01506b
Abstract: Here we report the conception, synthesis and evaluation of new hydrophilic rhodamine-based enzymatic substrates for detection of peptidase activity compatible with high-throughput screening using droplet-based microfluidics. read more here.
Keywords: enzymatic substrates; new hydrophilic; rhodamine based; droplet based ... See more keywords
A label-free LC/MS-based enzymatic activity assay for the detection of PDE5A inhibitors
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2023.1097027
Abstract: Phosphodiesterase type 5 (PDE5), a cyclic nucleotide phosphodiesterase, controls the duration of the cyclic guanosine monophosphate (cGMP) signal by hydrolyzing cGMP to GMP. Inhibiting the activity of PDE5A has proven to be an effective strategy… read more here.
Keywords: activity assay; pde5a inhibitors; activity; based enzymatic ... See more keywords