Development and application of novel BiFC probes for cell sorting based on epigenetic modification
Sign Up to like & getrecommendations! Published in 2022 at "Cytometry Part A"
DOI: 10.1002/cyto.a.24530
Abstract: The epigenetic signature of cancer cells varies with disease progression and drug treatment, necessitating the study of these modifications with single cell resolution over time. The rapid detection and sorting of cells based on their… read more here.
Keywords: application; development; application novel; based epigenetic ... See more keywords
Caenorhabditis elegans sperm carry a histone-based epigenetic memory of both spermatogenesis and oogenesis
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-06236-8
Abstract: Paternal contributions to epigenetic inheritance are not well understood. Paternal contributions via marked nucleosomes are particularly understudied, in part because sperm in some organisms replace the majority of nucleosome packaging with protamine packaging. Here we… read more here.
Keywords: based epigenetic; epigenetic memory; histone based; caenorhabditis elegans ... See more keywords
EXTH-31. Systematic identification of lipid nanoparticles for mRNA-based epigenetic and immune glioblastoma therapies
Sign Up to like & getrecommendations! Published in 2025 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noaf201.1365
Abstract: Messenger RNA-based therapeutics, including cancer vaccines and gene editors, have potential to revolutionize treatment of malignant gliomas. We recently adapted a CRISPR-based epigenetic editing therapeutic, CRISPRoff, to induce long-term silencing of MGMT in glioblastoma preclinical… read more here.
Keywords: mrna based; based epigenetic; delivery; glioblastoma ... See more keywords
Abstract 2618: Methylation-based epigenetic “switches” in group 3/4 medulloblastoma
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Research"
DOI: 10.1158/1538-7445.am2025-2618
Abstract: Medulloblastoma (MB) is the most common primary brain tumor in children, with group 3 and group 4 (G3/4) being the most aggressive. Methylation studies have identified eight distinct subgroups within G3/4 MB, with observed differences… read more here.
Keywords: methylation based; methylation; based epigenetic; group ... See more keywords
Changes in Loneliness, BDNF, and Biological Aging Predict Trajectories in a Blood-Based Epigenetic Measure of Cortical Aging: A Study of Older Black Americans
Sign Up to like & getrecommendations! Published in 2023 at "Genes"
DOI: 10.3390/genes14040842
Abstract: A recent epigenetic measure of aging has developed based on human cortex tissue. This cortical clock (CC) dramatically outperformed extant blood-based epigenetic clocks in predicting brain age and neurological degeneration. Unfortunately, measures that require brain… read more here.
Keywords: brain; epigenetic measure; based epigenetic; blood based ... See more keywords