Evaluation of the herbicide glyphosate, (aminomethyl)phosphonic acid, and glyphosate‐based formulations for genotoxic activity using in vitro assays
Sign Up to like & getrecommendations! Published in 2023 at "Environmental and Molecular Mutagenesis"
DOI: 10.1002/em.22534
Abstract: Glyphosate, the most heavily used herbicide world‐wide, is applied to plants in complex formulations that promote absorption. The National Toxicology Program reported in 1992 that glyphosate, administered to rats and mice at doses up to… read more here.
Keywords: phosphonic acid; glyphosate; aminomethyl phosphonic; glyphosate based ... See more keywords
Bridging the gaps between academic research and industrial product developments of lipid-based formulations.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced drug delivery reviews"
DOI: 10.1016/j.addr.2019.01.009
Abstract: Lipid-based formulations, including self-emulsifying drug delivery systems (SEDDS), are an interesting formulation technology that enables the clinical use of compounds for which a low aqueous solubility may be a limitation. From an academic perspective, the… read more here.
Keywords: based formulations; lipid based; gaps academic; academic research ... See more keywords
Advances in lipid carriers for drug delivery to the gastrointestinal tract
Sign Up to like & getrecommendations! Published in 2021 at "Current Opinion in Colloid and Interface Science"
DOI: 10.1016/j.cocis.2020.101414
Abstract: Abstract Lipid-based formulations have re-emerged as oral drug delivery systems. Advances in the techniques to evaluate the in vivo fate of the formulations, together with an improved knowledge of the gastrointestinal processes/barriers to the evolving lipid-based… read more here.
Keywords: based formulations; drug delivery; advances lipid; lipid based ... See more keywords
Development, characterization and evaluation of nanocarrier based formulations of antipsoriatic drug “acitretin” for skin targeting
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2020.102010
Abstract: Abstract Acitretin, a 2nd generation retinoid, is a drug of choice for the treatment of severe psoriasis. Presently, only capsule formulation for oral administration is commercially available and associated with limitations of severe systemic side… read more here.
Keywords: acitretin; skin targeting; microscopy; based formulations ... See more keywords
Digestion of Lipid-Based Formulations Not Only Mediates Changes to Absorption of Poorly Soluble Drugs Due to Differences in Solubilization But Also Reflects Changes to Thermodynamic Activity and Permeability.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.1c00015
Abstract: The aim of this study was to evaluate the effect of lipid digestion on the permeability and absorption of orally administered saquinavir (SQV), a biopharmaceutics classification system (BCS) class IV drug, in different lipid-based formulations.… read more here.
Keywords: based formulations; lipid based; sqv; digestion ... See more keywords
Montmorillonite and Laponite Clay Materials for the Solidification of Lipid-Based Formulations for the Basic Drug Blonanserin: In Vitro and in Vivo Investigations.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.8b00555
Abstract: Solid-state lipid-based formulations offer great potential for the improved oral delivery of poorly water-soluble drugs. This study investigates the use of the high-surface-area clay materials, montmorillonite and laponite, as solid carriers for lipid-based formulations. The… read more here.
Keywords: based formulations; lipid based; montmorillonite laponite; drug ... See more keywords
Comparative effectiveness of probiotic-based formulations on cecal microbiota modulation in broilers
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0225871
Abstract: The potential of probiotics to manipulate the intestinal microbial ecosystem toward commensal bacteria growth offers great opportunity for enhancing health and performance in poultry. This study aimed to evaluate the efficacy of five probiotic-based formulations… read more here.
Keywords: modulation; diversity; based formulations; probiotic based ... See more keywords
Nanomedicine-based formulations containing ω-3 polyunsaturated fatty acids: potential application in cardiovascular and neoplastic diseases
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s197499
Abstract: Omega-3 polyunsaturated fatty acids (ω-3 PUFAs) are dietary factors involved in the prevention of cardiovascular, inflammatory, and neoplastic diseases. A multidisciplinary approach – based on recent findings in nutritional science, lipid biochemistry, biotechnology, and biology… read more here.
Keywords: neoplastic diseases; polyunsaturated fatty; based formulations; nanomedicine based ... See more keywords
Polysaccharide-Based Formulations for Healing of Skin-Related Wound Infections: Lessons from Animal Models and Clinical Trials
Sign Up to like & getrecommendations! Published in 2019 at "Biomolecules"
DOI: 10.3390/biom10010063
Abstract: Skin injuries constitute a gateway for pathogenic bacteria that can be either part of tissue microbiota or acquired from the environmental. These microorganisms (such as Acinetobacter baumannii, Enterococcus faecalis, Pseudomonas aeruginosa, and Staphylococcus aureus) produce… read more here.
Keywords: formulations healing; models clinical; based formulations; skin ... See more keywords
Antibacterial and Antiviral Properties of Tetrahydrocurcumin-Based Formulations: An Overview of Their Metabolism in Different Microbiotic Compartments
Sign Up to like & getrecommendations! Published in 2022 at "Life"
DOI: 10.3390/life12111708
Abstract: In this review, the basic metabolic characteristics of the curcuminoid tetrahydrocurcumin (THC) at the level of the intestinal microbiota were addressed. Special attention was given to the bactericidal effects of one of the THC-phospholipid formulations,… read more here.
Keywords: antibacterial antiviral; properties tetrahydrocurcumin; antiviral properties; microbiotic compartments ... See more keywords
In Vitro Performance and Chemical Stability of Lipid-Based Formulations Encapsulated in a Mesoporous Magnesium Carbonate Carrier
Sign Up to like & getrecommendations! Published in 2020 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics12050426
Abstract: Lipid-based formulations can circumvent the low aqueous solubility of problematic drug compounds and increase their oral absorption. As these formulations are often physically unstable and costly to manufacture, solidification has been suggested as a way… read more here.
Keywords: magnesium carbonate; vitro performance; based formulations; lipid based ... See more keywords