Design and Synthesis of Pyrrolidine-based Fragments That Sample Three-dimensional Molecular Space.
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DOI: 10.1021/acsmedchemlett.9b00070
Abstract: Fragment-based drug discovery (FBDD) is a well-established technology for lead compound generation in drug discovery. As this technology has evolved, the design of fragments for screening has also evolved to engender not just an understanding… read more here.
Keywords: pyrrolidine based; design synthesis; based fragments; synthesis pyrrolidine ... See more keywords