Structure–Activity Relationship of Propargylamine‐Based HDAC Inhibitors
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DOI: 10.1002/cmdc.201700550
Abstract: As histone deacetylases (HDACs) play an important role in the treatment of cancer, their selective inhibition has been the subject of various studies. These continuous investigations have given rise to a large collection of pan‐… read more here.
Keywords: relationship propargylamine; propargylamine based; hdac inhibitors; activity relationship ... See more keywords
Quinazoline Based HDAC Dual Inhibitors as Potential Anti-Cancer Agents
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DOI: 10.3390/molecules27072294
Abstract: Cancer is the most devastating disease and second leading cause of death around the world. Despite scientific advancements in the diagnosis and treatment of cancer which can include targeted therapy, chemotherapy, endocrine therapy, immunotherapy, radiotherapy… read more here.
Keywords: cancer; dual inhibitors; anti cancer; quinazoline based ... See more keywords