SNP‐based heritability and selection analyses: Improved models and new results
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DOI: 10.1002/bies.202100170
Abstract: Complex‐trait genetics has advanced dramatically through methods to estimate the heritability tagged by SNPs, both genome‐wide and in genomic regions of interest such as those defined by functional annotations. The models underlying many of these… read more here.
Keywords: based heritability; heritability; heritability selection; snp based ... See more keywords
The SNP-Based Heritability — A Commentary on Yang et al. (2010)
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DOI: 10.1017/thg.2020.25
Abstract: Abstract I write this commentary as a part of a special issue published in this journal to celebrate Nick Martin’s contribution to the field of human genetics. In this commentary, I briefly describe the background… read more here.
Keywords: genetics; based heritability; yang 2010; snp based ... See more keywords
Assortative mating biases marker-based heritability estimators
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DOI: 10.1038/s41467-022-28294-9
Abstract: Many traits are subject to assortative mating, with recent molecular genetic findings confirming longstanding theoretical predictions that assortative mating induces long range dependence across causal variants. However, all marker-based heritability estimators implicitly assume mating is… read more here.
Keywords: marker based; assortative mating; based heritability; heritability estimators ... See more keywords