Enantioselective synthesis of C–C and C–N axially chiral pyrazole-based heterobiaryls
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DOI: 10.1039/d5sc06841j
Abstract: Axially chiral five-membered heteroaryls are prevalent in bioactive molecules. Their catalytic asymmetric synthesis remains challenging due to their relatively low rotational energy barriers. We developed a chiral nickel(ii) complex-catalyzed asymmetric cycloaddition/oxidation sequential reaction of hydrazonoyl… read more here.
Keywords: based heterobiaryls; enantioselective synthesis; pyrazole based; axially chiral ... See more keywords