Applying valency-based immuno-selection to generate broadly cross-reactive antibodies against influenza hemagglutinins
Sign Up to like & getrecommendations! Published in 2024 at "Nature Communications"
DOI: 10.1038/s41467-024-44889-w
Abstract: Conserved epitopes shared between virus subtypes are often subdominant, making it difficult to induce broadly reactive antibodies by immunization. Here, we generate a plasmid DNA mix vaccine that encodes protein heterodimers with sixteen different influenza… read more here.
Keywords: reactive antibodies; generate; based immuno; valency based ... See more keywords
Virus-Based Immuno-Oncology Models
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10061441
Abstract: Immunotherapy has been extensively explored in recent years with encouraging results in selected types of cancer. Such success aroused interest in the expansion of such indications, requiring a deep understanding of the complex role of… read more here.
Keywords: oncology; based immuno; immuno oncology; oncology models ... See more keywords