Dynamic microbiome and metabolome analyses reveal the interaction between gut microbiota and anti‐PD‐1 based immunotherapy in hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Cancer"
DOI: 10.1002/ijc.34118
Abstract: Hepatocellular carcinoma (HCC) is a severe disease with high mortality and global incidence. However, the interaction between the gut microbiome and combined immunotherapy for HCC is yet unclear. In this prospective clinical study, patients with… read more here.
Keywords: hepatocellular carcinoma; gut; interaction gut; based immunotherapy ... See more keywords
Bispecific light T-cell engagers for gene-based immunotherapy of epidermal growth factor receptor (EGFR)-positive malignancies
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-018-2181-5
Abstract: The recruitment of T-cells by bispecific antibodies secreted from adoptively transferred, gene-modified autologous cells has shown satisfactory results in preclinical cancer models. Even so, the approach’s translation into the clinic will require incremental improvements to… read more here.
Keywords: light cell; cell engagers; based immunotherapy; gene based ... See more keywords
Effect of dendritic cell-based immunotherapy on hepatocellular carcinoma: A systematic review and meta-analysis.
Sign Up to like & getrecommendations! Published in 2018 at "Cytotherapy"
DOI: 10.1016/j.jcyt.2018.06.002
Abstract: BACKGROUND AIMS Dendritic cell (DC)-based immunotherapy has recently been reported frequently in the treatment of hepatocellular carcinoma (HCC); however, its efficacy remains controversial. In this study, we aimed to evaluate the clinical efficacy of DC-based… read more here.
Keywords: hepatocellular carcinoma; hcc; immunotherapy; cell based ... See more keywords
Dendritic Cell-Based Immunotherapy for Solid Tumors12
Sign Up to like & getrecommendations! Published in 2018 at "Translational Oncology"
DOI: 10.1016/j.tranon.2018.03.007
Abstract: As a treatment for solid tumors, dendritic cell (DC)-based immunotherapy has not been as effective as expected. Here, we review the reasons underlying the limitations of DC-based immunotherapy for solid tumors and ask what can… read more here.
Keywords: solid tumors; cell based; based immunotherapy; cell ... See more keywords
Prospects for antimicrobial peptide-based immunotherapy approaches in Leishmania control
Sign Up to like & getrecommendations! Published in 2018 at "Expert Review of Anti-infective Therapy"
DOI: 10.1080/14787210.2018.1483720
Abstract: ABSTRACT Introduction: Leishmaniasis is one of the neglected tropical diseases and is highly endemic in many countries. Currently, there is no adequate human vaccine and treatment to control the disease. Areas covered: As a result… read more here.
Keywords: prospects antimicrobial; leishmaniasis; control; peptide based ... See more keywords
Nanoparticle-based immunotherapy: state of the art and future perspectives
Sign Up to like & getrecommendations! Published in 2020 at "Expert Review of Clinical Immunology"
DOI: 10.1080/1744666x.2020.1762572
Abstract: ABSTRACT Introduction For several years now, medicine has been benefiting from the contribution of nanoparticles (NPs) technology for both diagnosis and therapy. They can be used as adjuvants, being capable per se of immune-modulating activity,… read more here.
Keywords: nanoparticle based; state art; immunotherapy state; ait ... See more keywords
HLA ligandome analysis of primary chronic lymphocytic leukemia (CLL) cells under lenalidomide treatment confirms the suitability of lenalidomide for combination with T-cell-based immunotherapy
Sign Up to like & getrecommendations! Published in 2018 at "OncoImmunology"
DOI: 10.1080/2162402x.2017.1316438
Abstract: ABSTRACT Recent studies suggest that CLL is an immunogenic disease, which might be effectively targeted by antigen-specific T-cell-based immunotherapy. However, CLL is associated with a profound immune defect, which might represent a critical limitation for… read more here.
Keywords: cll; cell based; lenalidomide treatment; based immunotherapy ... See more keywords
Trial watch: Dendritic cell (DC)-based immunotherapy for cancer
Sign Up to like & getrecommendations! Published in 2022 at "Oncoimmunology"
DOI: 10.1080/2162402x.2022.2096363
Abstract: ABSTRACT Dendritic cell (DC)-based vaccination for cancer treatment has seen considerable development over recent decades. However, this field is currently in a state of flux toward niche-applications, owing to recent paradigm-shifts in immuno-oncology mobilized by… read more here.
Keywords: cell based; cell; based immunotherapy; dendritic cell ... See more keywords
Neoadjuvant anti-PD-1-based immunotherapy: evolving a new standard of care
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DOI: 10.1136/jitc-2024-010833
Abstract: Neoadjuvant (presurgical) anti-programmed cell death protein-1 (PD-1)-based immunotherapy as a new approach to cancer treatment has been developing on an accelerated trajectory since the seminal clinical trial results from studies in lung cancer and melanoma… read more here.
Keywords: based immunotherapy; cancer; neoadjuvant anti; anti based ... See more keywords
Dendritic Cell-Based Immunotherapy: The Importance of Dendritic Cell Migration
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Immunology Research"
DOI: 10.1155/2024/7827246
Abstract: Dendritic cells (DCs) are specialized antigen-presenting cells that are crucial for maintaining self-tolerance, initiating immune responses against pathogens, and patrolling body compartments. Despite promising aspects, DC-based immunotherapy faces challenges that include limited availability, immune escape… read more here.
Keywords: importance; based immunotherapy; cell based; migration ... See more keywords
Abstract 5183: Development of an aerosol-based immunotherapy for lung cancer
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-5183
Abstract: Lung cancer is one of the leading causes of cancer death and the second most cancer in the world. Compared to systematic administration, local delivery of therapeutic agents to the lung increases their accumulation in… read more here.
Keywords: lung cancer; based immunotherapy; development aerosol; lung ... See more keywords