Synthesis, Molecular Docking Analysis and in Vitro Biological Evaluation of Some New Heterocyclic Scaffolds-Based Indole Moiety as Possible Antimicrobial Agents
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2021.775013
Abstract: In the present study, a general approach for the synthesis of 1-(1H-indol-3-yl)-3,3-dimercaptoprop-2-en-1-one (1) and 5-(1H-indol-3-yl)-3H-1,2-dithiole-3-thione (2) was performed. They are currently used as efficient precursors for the synthesis of some new compounds bearing five- and/or… read more here.
Keywords: molecular docking; based indole; docking analysis; synthesis molecular ... See more keywords
Synthesis, Characterization, Antibacterial Activity And Molecular Docking Studies Of Novel Nitrogen Based Indole-2-One Schiff’s Bases
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Pharmaceutical Negative Results"
DOI: 10.47750/pnr.2022.13.s08.654
Abstract: Series of some novel nitrogen based Indole-2-one Schiff’s bases (4a-4j) were synthesized by a conventional method via Schiff’s bases mechanism. The Istain Schiff’s bases was made by combining substituted isatin with hydrazine hydrate in ethanol… read more here.
Keywords: schiff bases; based indole; schiff; novel nitrogen ... See more keywords