Anticancer Compounds Based on Isatin-Derivatives: Strategies to Ameliorate Selectivity and Efficiency
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DOI: 10.3389/fmolb.2020.627272
Abstract: In this review we compare and discuss results of compounds already reported as anticancer agents based on isatin-derivatives, metalated as well as non-metallated. Isatin compounds can be obtained from plants, marine animals, and is also… read more here.
Keywords: anticancer compounds; based isatin; isatin derivatives; compounds based ... See more keywords
Investigations on Anticancer Potentials by DNA Binding and Cytotoxicity Studies for Newly Synthesized and Characterized Imidazolidine and Thiazolidine-Based Isatin Derivatives
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DOI: 10.3390/molecules27020354
Abstract: Imidazolidine and thiazolidine-based isatin derivatives (IST-01–04) were synthesized, characterized, and tested for their interactions with ds-DNA. Theoretical and experimental findings showed good compatibility and indicated compound–DNA binding by mixed mode of interactions. The evaluated binding… read more here.
Keywords: cell; based isatin; dna binding; imidazolidine thiazolidine ... See more keywords