Anthraquinone-based Ligand as MNase Inhibitor: Insights from Inhibition Studies and Generation of a Payload Nanocarrier for Potential Anti-MRSA Therapy.
Sign Up to like & getrecommendations! Published in 2023 at "ChemMedChem"
DOI: 10.1002/cmdc.202200711
Abstract: The present study highlights the prospect of an anthraquinone-based ligand (C1) as an inhibitor of micrococcal nuclease (MNase) enzyme secreted by Staphylococcus aureus. MNase inhibition rendered by 5.0 µM C1 was ~96% and the ligand… read more here.
Keywords: inhibition; mnase; based ligand; anthraquinone based ... See more keywords
Identification of Potential Inhibitors of the SARS‐CoV‐2 NSP13 Helicase via Structure‐Based Ligand Design, Molecular Docking and Nonequilibrium Alchemical Simulations
Sign Up to like & getrecommendations! Published in 2024 at "ChemMedChem"
DOI: 10.1002/cmdc.202400095
Abstract: We have assembled a computational pipeline based on virtual screening, docking techniques, and nonequilibrium molecular dynamics simulations, with the goal of identifying possible inhibitors of the SARS‐CoV‐2 NSP13 helicase, catalyzing by ATP hydrolysis the unwinding… read more here.
Keywords: sars cov; structure based; cov nsp13; nsp13 helicase ... See more keywords
Experimental and theoretical insights into spectroscopy and electrochemistry of Re(I) carbonyl with oxazoline-based ligand
Sign Up to like & getrecommendations! Published in 2019 at "Polyhedron"
DOI: 10.1016/j.poly.2019.06.047
Abstract: Abstract Structural, spectroscopic and electrochemical properties of a novel rhenium(I) carbonyl complex with oxazoline-based ligand, 2-(4,5-dihydro-2-oxazolyl)quinoline (quinox), are discussed herein. The molecular formula of the title compound fac–[ReCl(CO)3(quinox)] was determined by X-ray analysis and confirmed… read more here.
Keywords: electrochemistry; spectroscopy; based ligand; oxazoline based ... See more keywords
Oxidovanadium (V and IV) complexes incorporating coumarin based O^N^O ligand: Synthesis, structure and catalytic activities
Sign Up to like & getrecommendations! Published in 2020 at "Polyhedron"
DOI: 10.1016/j.poly.2019.114241
Abstract: Abstract The tridentate ligand H2L1, [(E)-7-Hydroxy-8-[(2-hydroxy-phenylimino)-methyl]-4-methyl-chromen-2-one] has been used in the present work towards the synthesis of mononuclear oxidovanadium complexes. Three mononuclear complexes [VOL1(OMe)(MeOH)], 1; [VO(L1)(8-Hq)], 2 and [VO(L1)(1,10-phen)], 3 have been successfully synthesized with… read more here.
Keywords: coumarin based; oxidovanadium complexes; complexes incorporating; incorporating coumarin ... See more keywords
Fabrication of metal coordination-synergistic magnetic imprinted microspheres based on ligand-free Fe3O4-Cu for specific recognition of bovine hemoglobin.
Sign Up to like & getrecommendations! Published in 2021 at "Talanta"
DOI: 10.1016/j.talanta.2021.122496
Abstract: In this work, a synergistic imprinting strategy combined with metal coordination based on ligand-free Fe3O4-Cu was proposed to fabricate molecularly imprinted polymers (MIPs) for the recognition and isolation of bovine hemoglobin (BHb) specifically in biological… read more here.
Keywords: adsorption; ligand free; metal; based ligand ... See more keywords
An Anionic Indium-Organic Framework with Spirobifluorene-Based Ligand for Selective Adsorption of Organic Dyes.
Sign Up to like & getrecommendations! Published in 2021 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.0c02962
Abstract: Ionic metal-organic frameworks (MOFs) with an ionic skeleton and unique porous structures could selectively adsorb charged dyes with specific dimensions. However, the ion-exchange-based and size-exclusion-based process as a chromatography method needs to be further explored.… read more here.
Keywords: adsorption; organic dyes; selective adsorption; spirobifluorene based ... See more keywords
Nitric Oxide Reactivity of a Cu(II) Complex of an Imidazole-Based Ligand: Aromatic C-Nitrosation Followed by the Formation of N-Nitrosohydroxylaminato Complex.
Sign Up to like & getrecommendations! Published in 2017 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.7b00069
Abstract: A binuclear Cu(II) complex, 1, [Cu2(L-)2(OAc)](OAc) of imidazole-based ligand LH {LH = 2-(bis(2-ethyl-5-methyl-1H-imidazol-4-yl)methyl)phenol} was synthesized and characterized spectroscopically and structurally. Addition of an equivalent amount of nitric oxide (NO) by a gastight syringe to the… read more here.
Keywords: methyl; nitrosohydroxylaminato complex; based ligand; nitric oxide ... See more keywords
Spacer Matters: All-Peptide-Based Ligand for Promoting Interfacial Proteolysis and Plasmonic Coupling.
Sign Up to like & getrecommendations! Published in 2022 at "Nano letters"
DOI: 10.1021/acs.nanolett.2c03052
Abstract: Plasmonic coupling via nanoparticle assembly is a popular signal-generation method in bioanalytical sensors. Here, we customized an all-peptide-based ligand that carries an anchoring group, polyproline spacer, biomolecular recognition, and zwitterionic domains for functionalizing gold nanoparticles… read more here.
Keywords: peptide based; plasmonic coupling; ligand; spacer ... See more keywords
Tetrazine-Based Ligand Transformation Driving Metal–Metal Bond and Mixed-Valence HgI/HgII
Sign Up to like & getrecommendations! Published in 2018 at "ACS Omega"
DOI: 10.1021/acsomega.8b01861
Abstract: Understanding the self-assembly of cluster aggregates remains an important challenge in coordination chemistry. A chelating tetrazine-based ligand was employed to isolate an unprecedented tetranuclear Hg4 complex exhibiting HgI/HgII mixed valence, which also contains metal–metal bonds.… read more here.
Keywords: tetrazine based; metal; based ligand; mixed valence ... See more keywords
A new heptadentate picolinate-based ligand and its corresponding Gd(iii) complex: the effect of pendant picolinate versus acetate on complex properties.
Sign Up to like & getrecommendations! Published in 2017 at "Dalton transactions"
DOI: 10.1039/c7dt04150k
Abstract: To attain high relaxivity as well as stability, a new water-soluble, water-coordinated Gd(iii) complex, which was synthesised by reacting equimolar amounts of picolinate-based ligand H4peada and GdCl3·xH2O at pH ∼ 6.5, was examined. The number… read more here.
Keywords: picolinate; complex; picolinate based; based ligand ... See more keywords
Hydrogen peroxide assisted photorelease of an anthraquinone-based ligand from [Ru(2,2'-bipyridine)2(9,10-dioxo-9,10-dihydroanthracen-1-olate)]Cl in aqueous solution.
Sign Up to like & getrecommendations! Published in 2020 at "Dalton transactions"
DOI: 10.1039/d0dt02339f
Abstract: A new class of light-activated ruthenium(ii) complex was designed as a potential blocker of biological functioning, especially for targeting redox reactions within mitochondria under light activation. Based on our concepts the complex [Ru(bipy)2(1-hydroxyanthra-9,10 quinone)]Cl (RU1)… read more here.
Keywords: photorelease anthraquinone; hydrogen peroxide; assisted photorelease; based ligand ... See more keywords