l-Lysine based lipidated biphenyls as agents with anti-biofilm and anti-inflammatory properties that also inhibit intracellular bacteria.
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DOI: 10.1039/c7cc04206j
Abstract: l-Lysines were conjugated to lipidated biphenyls using simple synthetic chemistry to obtain selective membrane-active antibacterial agents that inhibit cell-wall biosynthesis. The most selective compound bore promising activity against biofilm-related infections and intracellular bacteria, and also… read more here.
Keywords: intracellular bacteria; lysine based; based lipidated; lipidated biphenyls ... See more keywords