Immune-checkpoint inhibitor therapy response evaluation using oncophysics-based mathematical models.
Sign Up to like & getrecommendations! Published in 2022 at "Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology"
DOI: 10.1002/wnan.1855
Abstract: The field of oncology has transformed with the advent of immunotherapies. The standard of care for multiple cancers now includes novel drugs that target key checkpoints that function to modulate immune responses, enabling the patient's… read more here.
Keywords: oncophysics based; checkpoint inhibitor; immune checkpoint; based mathematical ... See more keywords
Novel 1,3,4-thiadiazoles inhibit colorectal cancer via blockade of IL-6/COX-2 mediated JAK2/STAT3 signals as evidenced through data-based mathematical modeling.
Sign Up to like & getrecommendations! Published in 2018 at "Cytokine"
DOI: 10.1016/j.cyto.2018.03.026
Abstract: We attempted a preclinical study using DMH-induced CRC rat model to evaluate the antitumor potential of our recently synthesized 1,3,4-thiadiazoles. The molecular insights were confirmed through ELISA, qRT-PCR and western blot analyses. The CRC condition… read more here.
Keywords: jak2 stat3; based mathematical; mathematical modeling; cox ... See more keywords
An artificial neural network-based mathematical model for the prediction of blast-induced ground vibrations
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Environmental Studies"
DOI: 10.1080/00207233.2019.1662186
Abstract: ABSTRACT This paper presents an artificial neural network (ANN) based mathematical model for the prediction of blast-induced ground vibrations using the data obtained from the literature. A feed-forward back-propagation multi-layer perceptron (MLP) was adopted, and… read more here.
Keywords: neural network; network; based mathematical; model ... See more keywords
Comparison between chikungunya and dengue viruses transmission based on a mathematical model
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Biomathematics"
DOI: 10.1142/s1793524517500875
Abstract: Chikungunya and dengue viruses are transmitted by mosquitoes of genus Aedes. Based on a mathematical model dealing with arboviruses transmission that encompasses human and mosquito populations, the risks of dengue and chikungunya infections are compared.… read more here.
Keywords: chikungunya dengue; based mathematical; chikungunya; mathematical model ... See more keywords