Articles with "based metallonucleases" as a keyword



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Copper based metallonucleases as potential antitumor drugs: Synthesis, Structure, in vitro Cytotoxicity and Apoptosis inducing properties

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Published in 2021 at "Journal of Molecular Structure"

DOI: 10.1016/j.molstruc.2021.130278

Abstract: Abstract The new polypyridyl ligands L1 and L2 {L1 =4,4′-oxybis(N,N-bis(pyridin- 2-ylmethyl)aniline); L2 = 4-methyl-N, N-bis(pyridin- 2-ylmethyl)aniline} and three relevant di-, mono-nucleating Cu(II) complexes [Cu2L1Cl4]2 (1), [CuL2Cl2]2•4H2O (2) and [Cu2(L2)2(μ-Cl)2] (ClO4)2 (3) have been synthesized as anticancer agents.… read more here.

Keywords: cytotoxicity; structure; apoptosis inducing; copper based ... See more keywords