Phylogenetic tree-based microbiome association test
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DOI: 10.1093/bioinformatics/btz686
Abstract: MOTIVATION Ecological patterns of the human microbiota exhibit high inter-subject variation, with few operational taxonomic units (OTUs) shared across individuals. To overcome these issues, non-parametric approaches, such as the Mann-Whitney U-test and Wilcoxon rank-sum test,… read more here.
Keywords: test; association; tree based; based microbiome ... See more keywords
CSMD: a computational subtraction-based microbiome discovery pipeline for species-level characterization of clinical metagenomic samples
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DOI: 10.1093/bioinformatics/btz790
Abstract: MOTIVATION Microbiome analyses of clinical samples with low microbial biomass are challenging because of the very small quantities of microbial DNA relative to the human host, ubiquitous contaminating DNA in sequencing experiments, and the large… read more here.
Keywords: csmd computational; pipeline; subtraction based; computational subtraction ... See more keywords