Recent Advances on cell Culture Platforms for in vitro Drug Screening and Cell Therapies: From Conventional to Microfluidic Strategies.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202202936
Abstract: The clinical translations of drugs and nanomedicines depend on coherent pharmaceutical research based on biologically accurate screening approaches. Since establishing the 2D in vitro cell culture method, the scientific community has improved cell-based drug screening… read more here.
Keywords: drug screening; cell culture; cell; based microfluidics ... See more keywords
Fluid mixing in droplet‐based microfluidics with T junction and convergent–divergent sinusoidal microchannels
Sign Up to like & getrecommendations! Published in 2018 at "ELECTROPHORESIS"
DOI: 10.1002/elps.201700374
Abstract: To explore and utilize the advantages of droplet‐based microfluidics, hydrodynamics, and mixing process within droplets traveling though the T junction channel and convergent–divergent sinusoidal microchannels are studied by numerical simulations and experiments, respectively. In the… read more here.
Keywords: droplet; effect; convergent divergent; based microfluidics ... See more keywords
Droplet‐based microfluidics systems in biomedical applications
Sign Up to like & getrecommendations! Published in 2019 at "ELECTROPHORESIS"
DOI: 10.1002/elps.201900047
Abstract: Microfluidics has made a very impressive progress in the past decades due to its unique and instinctive advantages. Droplet‐based microfluidic systems show excellent compatibility with many chemical and biological reagents and are capable of performing… read more here.
Keywords: based microfluidics; droplet based; systems biomedical; microfluidics systems ... See more keywords
Vessel-on-a-chip with Hydrogel-based Microfluidics.
Sign Up to like & getrecommendations! Published in 2018 at "Small"
DOI: 10.1002/smll.201802368
Abstract: Hydrogel structures equipped with internal microchannels offer more in vivo-relevant models for construction of tissues and organs in vitro. However, currently used microfabrication methods of constructing microfluidic devices are not suitable for the handling of… read more here.
Keywords: vessel chip; hydrogel; chip hydrogel; hydrogel based ... See more keywords
Droplet-Based Microfluidics Digital PCR for the Detection of KRAS Mutations.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6734-6_12
Abstract: We demonstrate an accurate and sensitive quantification of mutated KRAS oncogene in genomic DNA, using droplet-based microfluidics and digital PCR. read more here.
Keywords: detection kras; based microfluidics; microfluidics digital; digital pcr ... See more keywords
Programmable paper-based microfluidics device with prefabricated patterns for prototyping of µPADs
Sign Up to like & getrecommendations! Published in 2019 at "Microfluidics and Nanofluidics"
DOI: 10.1007/s10404-019-2233-y
Abstract: In this paper, a new programmable structure of paper-based analytical devices and its programming method are represented to be used for the purpose of rapid prototyping without involving the fabrication process. The proposed ready-to-program structure… read more here.
Keywords: programmable paper; paper; device; based microfluidics ... See more keywords
Recent developments of droplets-based microfluidics for bacterial analysis
Sign Up to like & getrecommendations! Published in 2021 at "Chinese Chemical Letters"
DOI: 10.1016/j.cclet.2021.08.096
Abstract: ABSTRACT Droplet-based microfluidics enables the generation of uniform microdroplets at picoliter or nanoliter scale with high frequency (∼kHz) under precise control. The droplets can function as bioreactors for versatile chemical/biological study and analysis. Taking advantage… read more here.
Keywords: analysis; recent developments; developments droplets; based microfluidics ... See more keywords
Sorting Technology for Circulating Tumor Cells Based on Microfluidics.
Sign Up to like & getrecommendations! Published in 2020 at "ACS combinatorial science"
DOI: 10.1021/acscombsci.0c00157
Abstract: Circulating tumor cells (CTCs) carry reliable clinical information for the diagnosis and treatment of cancer that is a malignant disease with a high mortality rate. However, the amount of CTCs in the blood is quite… read more here.
Keywords: sorting technology; circulating tumor; tumor cells; based microfluidics ... See more keywords
Micropipette-powered droplet based microfluidics.
Sign Up to like & getrecommendations! Published in 2018 at "Biomicrofluidics"
DOI: 10.1063/1.5037795
Abstract: Droplet-based microfluidics, using water-in-oil emulsion droplets as micro-reactors, is becoming a widespread method for performing assays and especially in the cell biology field. Making a simple and highly portable system for creating emulsion droplets would… read more here.
Keywords: droplet; micropipette; micropipette powered; based microfluidics ... See more keywords
Droplet-based microfluidics as a future tool for strain improvement in lactic acid bacteria.
Sign Up to like & getrecommendations! Published in 2018 at "FEMS microbiology letters"
DOI: 10.1093/femsle/fny258
Abstract: Strain development is frequently used to improve the performance and functionality of industrially important microbes. As traditional mutagenesis screen is especially utilized by the food industry to improve strains used in food fermentation, high-throughput and… read more here.
Keywords: based microfluidics; droplet based; acid bacteria; strain improvement ... See more keywords
Rapid identification and quantitation of single plant seed allergen using paper-based microfluidics
Sign Up to like & getrecommendations! Published in 2022 at "PLOS ONE"
DOI: 10.1371/journal.pone.0266775
Abstract: Nucleic acid amplification is a sensitive and powerful tool for allergen detection. However, it is limited due to the relatively cumbersome methods required to extract nucleic acids from single plant seed allergen (e.g. peanut and… read more here.
Keywords: paper based; based microfluidics; seed allergen; plant seed ... See more keywords