An Expeditious Approach for the Synthesis of β‐Carboline−Pyrazole‐Based Molecular Hybrids
Sign Up to like & getrecommendations! Published in 2018 at "Asian Journal of Organic Chemistry"
DOI: 10.1002/ajoc.201700545
Abstract: A simple and highly efficient one-pot metal-free approach has been devised for the synthesis of β-carboline and pyrazole/pyrazoline based molecular hybrids. The synthesis of β-carboline C-1 tethered (N-acetyl)pyrazolines was achieved via cyclo-condensation approach while β-carboline… read more here.
Keywords: carboline pyrazole; based molecular; synthesis carboline; carboline ... See more keywords
Identification of new IDH2R140Q inhibitors by discriminatory analysis‐based molecular docking and biological evaluation
Sign Up to like & getrecommendations! Published in 2020 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202000063
Abstract: Isocitrate dehydrogenase 2 (IDH2) is a key enzyme in the regulation of cell metabolism. Its mutated type can lead to the accumulation of 2‐hydroxyglutarate, which is often related to malignancies such as acute myeloid leukemia.… read more here.
Keywords: new idh2r140q; analysis based; idh2r140q inhibitors; based molecular ... See more keywords
Triptycene-Based Molecular Rods for Langmuir-Blodgett Monolayers.
Sign Up to like & getrecommendations! Published in 2022 at "ChemPlusChem"
DOI: 10.1002/cplu.202200023
Abstract: Herein we introduce fully modular synthesis leading to three representative examples of rigid molecular rods that are intended to form sturdy monolayers on various surfaces. These molecules contain two triptycene units that are designed to… read more here.
Keywords: rods langmuir; langmuir blodgett; blodgett monolayers; molecular rods ... See more keywords
Ferroptosis‐based molecular prognostic model for adrenocortical carcinoma based on least absolute shrinkage and selection operator regression
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24465
Abstract: This study aimed to find ferroptosis‐related genes linked to clinical outcomes of adrenocortical carcinoma (ACC) and assess the prognostic value of the model. read more here.
Keywords: ferroptosis based; based molecular; model; adrenocortical carcinoma ... See more keywords
Imaging‐Based Molecular Characterization of Adult‐Type Diffuse Glioma Using Diffusion and Perfusion MRI in Pre‐ and Post‐Treatment Stage Considering Spatial and Temporal Heterogeneity
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.29781
Abstract: Imaging‐based molecular characterization is important for identifying treatment targets in adult‐type diffuse gliomas. read more here.
Keywords: adult type; imaging based; based molecular; type diffuse ... See more keywords
Design and development of pyrazol‐5‐ylbenzamide derivatives containing chiral oxazoline moiety as fungicides based on molecular docking
Sign Up to like & getrecommendations! Published in 2025 at "Pest Management Science"
DOI: 10.1002/ps.8663
Abstract: Development of novel chiral antifungal agents for effective control of plant pathogens is urgently needed. In this study, a series of pyrazol‐5‐yl‐benzamide derivatives containing chiral oxazoline moiety were rationally designed and developed based on molecular… read more here.
Keywords: molecular docking; derivatives containing; containing chiral; chiral oxazoline ... See more keywords
Feature-Based Molecular Networking for Metabolite Annotation.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0239-3_13
Abstract: The Global Natural Product Social Molecular Networking (GNPS) platform leverages tandem mass spectrometry (MS/MS) data for annotation of compounds. Molecular networks aid in the visualization of the chemical space within a metabolomics experiment. Recently, molecular… read more here.
Keywords: feature; annotation; based molecular; feature based ... See more keywords
Non-targeted metabolomics-based molecular networking enables the chemical characterization of Rumex sanguineus, a wild edible plant
Sign Up to like & getrecommendations! Published in 2025 at "Metabolomics"
DOI: 10.1007/s11306-024-02210-2
Abstract: Rumex sanguineus, a traditional medicinal plant of the Polygonaceae family, is gaining popularity as an edible resource. However, despite its historical and nutritional significance, its chemical composition remains poorly understood. To deepen the understanding of… read more here.
Keywords: rumex; plant; rumex sanguineus; based molecular ... See more keywords
Evolutionary relationships of Bresadolia (Basidiomycota, Polyporales) based on molecular and morphological evidence
Sign Up to like & getrecommendations! Published in 2018 at "Mycological Progress"
DOI: 10.1007/s11557-018-1416-3
Abstract: In the last decades, several phylogenetic studies have shown that Polyporus is polyphyletic; accordingly, several genera have been newly described or reinstated. Nevertheless, the phylogenetic position of many species in the genus remains highly contentious,… read more here.
Keywords: evolutionary relationships; bresadolia basidiomycota; relationships bresadolia; based molecular ... See more keywords
Quantitative analysis of autophagy-related protein LC3B by quantum-dot-based molecular imaging.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in cell biology"
DOI: 10.1016/bs.mcb.2020.12.007
Abstract: Autophagy is a process that facilitates the maintenance of intracellular homeostasis by removing unnecessary or dysfunctional cellular components. It plays a role in inhibiting tumorigenesis in the early stage of the disease and might promote… read more here.
Keywords: dot based; quantum dot; lc3b; based molecular ... See more keywords
A novel gold nanoparticles decorated magnetic microbead-based molecular beacon for DNA multiplexing detection by flow cytometry.
Sign Up to like & getrecommendations! Published in 2020 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2020.02.063
Abstract: Gold nanoparticles-based molecular beacon (Au NPs-MB), due to its extraordinary highly-quenching efficiency for fluorophores, has been extensively investigated and widely used for bioimaging and bioassay. However, apart from irreversible aggregation during the "aging" step, the… read more here.
Keywords: detection; gold nanoparticles; dna; molecular beacon ... See more keywords