Geometric trade-off between contractile force and viscous drag determines the actomyosin-based motility of a cell-sized droplet
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2121147119
Abstract: Significance Micrometer-scale small active systems, ranging from cells migrating through viscoelastic tissues to self-propelled droplets in microfluidic platforms, are often subject to environmental confinement. Growing evidence suggests that such confined environments are an essential factor… read more here.
Keywords: based motility; cell; cell sized; force ... See more keywords
WIPF2 promotes Shigella flexneri actin‐based motility and cell‐to‐cell spread
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DOI: 10.1111/cmi.13098
Abstract: Shigella flexneri is an intracellular pathogen that disseminates in colonic epithelial cells through actin‐based motility and formation of membrane protrusions at cell–cell contacts, that project into adjacent cells and resolve into vacuoles, from which the… read more here.
Keywords: based motility; cell cell; actin based; flexneri ... See more keywords
Regulator of Actin-Based Motility (RoaM) Downregulates Actin Tail Formation by Rickettsia rickettsii and Is Negatively Selected in Mammalian Cell Culture
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DOI: 10.1128/mbio.00353-22
Abstract: The mechanism of actin-based motility of spotted fever group Rickettsia has been studied extensively, but here, we provide genetic evidence that motility is a regulated process in R. rickettsii. The findings also suggest that serial… read more here.
Keywords: based motility; rickettsii; actin; motility ... See more keywords
Burkholderia pseudomallei BimC Is Required for Actin-Based Motility, Intracellular Survival, and Virulence
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DOI: 10.3389/fcimb.2019.00063
Abstract: The intracellular pathogen Burkholderia pseudomallei, the etiological agent of melioidosis in humans and various animals, is capable of survival and movement within the cytoplasm of host cells by a process known as actin-based motility. The… read more here.
Keywords: based motility; actin based; intracellular survival; bimc ... See more keywords
The relative binding position of Nck and Grb2 adaptors impacts actin-based motility of Vaccinia virus
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DOI: 10.7554/elife.74655
Abstract: Phosphotyrosine (pTyr) motifs in unstructured polypeptides orchestrate important cellular processes by engaging SH2-containing adaptors to assemble complex signalling networks. The concept of phase separation has recently changed our appreciation of multivalent networks, however, the role… read more here.
Keywords: nck grb2; based motility; ptyr; ptyr motifs ... See more keywords