Abstract 4117: Novel bead-based multiplex assay for the quantification of human immune checkpoint biomarkers
Sign Up to like & getrecommendations! Published in 2019 at "Immunology"
DOI: 10.1158/1538-7445.am2019-4117
Abstract: Immune checkpoint molecules are important regulators of immune activation. This regulation is critical to maintaining immune homeostasis, and is driven by a complex interplay of both co-stimulatory and inhibitory signals. These checkpoints are key to… read more here.
Keywords: checkpoint; multiplex assay; immune checkpoint; checkpoint biomarkers ... See more keywords
Expression of in vivo biotinylated recombinant antigens SAG1 and SAG2A from Toxoplasma gondii for improved seroepidemiological bead-based multiplex assays
Sign Up to like & getrecommendations! Published in 2020 at "BMC Biotechnology"
DOI: 10.1186/s12896-020-00646-7
Abstract: Background Few bead-based multiplex assays have been described that detect antibodies against the protozoan parasite Toxoplasma gondii in large-scale seroepidemiological surveys. Moreover, each multiplex assay has specific variations or limitations, such as the use of… read more here.
Keywords: bead based; sag1 sag2a; gondii; expression ... See more keywords
Blood-based multiplex kinase activity profiling as a predictive marker for clinical response to checkpoint blockade in advanced melanoma.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.9579
Abstract: 9579Background: Prediction of clinical responses to checkpoint inhibitor therapies is urgently needed. Notably, a significant proportion of patients does not benefit from the treatment, agents are ... read more here.
Keywords: profiling predictive; kinase activity; multiplex kinase; blood based ... See more keywords
Serum-based multiplex protein assay for early detection of colorectal cancer and precancerous lesions in a FIT positive population.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.e16145
Abstract: e16145Background: Colorectal cancer (CRC) is the second leading cancer worldwide in terms of incidence, 5-year prevalence and mortality for both women and men ages 45 years old and up. The current ... read more here.
Keywords: colorectal cancer; protein assay; serum based; multiplex protein ... See more keywords
Timely and Blood-Based Multiplex Molecular Profiling of Acute Stroke
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DOI: 10.3390/life11080816
Abstract: Stroke is a leading cause of death and disability in the world. To address such a problem, early diagnosis and tailored acute treatment represent one of the major priorities in acute stroke care. Since the… read more here.
Keywords: acute stroke; timely blood; blood based; care ... See more keywords