Lipid-based Nanocarriers Enabled Oral Delivery of Oleanolic Acid Derivative DKS26 for Diabetes Management.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202300639
Abstract: Oleanolic acid (OA, (3β)-3-hydroxy-oleanol-12-en-28-oic acid) derivative DKS26 has hypolipidemic, islet and hepatoprotective effects. However, high lipophilicity and low water solubility of DKS26 led to its extremely low oral bioavailability. Herein, lipid-based nanocarriers, including lipid nanodiscs… read more here.
Keywords: dks26; lipid based; acid derivative; based nanocarriers ... See more keywords
Ligand conjugated lipid‐based nanocarriers for cancer theranostics
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.28205
Abstract: Cancer is one of the major health‐related issues affecting the population worldwide and subsequently accounts for the second‐largest death. Genetic and epigenetic modifications in oncogenes or tumor suppressor genes affect the regulatory systems that lead… read more here.
Keywords: conjugated lipid; lipid based; ligand conjugated; cancer ... See more keywords
Current approaches in lipid-based nanocarriers for oral drug delivery
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DOI: 10.1007/s13346-021-00908-7
Abstract: Graphical abstract Lipid-based nanocarriers have gained much interest as carriers of drugs with poor oral bioavailability because of their remarkable advantages like low toxicity, affordable scale-up manufacture, strong biocompatibility or high drug loading efficiency. The… read more here.
Keywords: drug delivery; lipid based; oral drug; based nanocarriers ... See more keywords
Carbohydrate-based nanocarriers and their application to target macrophages and deliver antimicrobial agents.
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DOI: 10.1016/j.addr.2019.09.002
Abstract: Many deadly infections are produced by microorganisms capable of sustained survival in macrophages. This reduces exposure to chemotherapy, prevents immune detection, and is akin to criminals hiding in police stations. Therefore, the use of glyco-nanoparticles… read more here.
Keywords: carbohydrate based; application target; based nanocarriers; drug ... See more keywords
3P Determination of therapeutic effects of multifunctional micelle-based nanocarriers on breast cancer cells
Sign Up to like & getrecommendations! Published in 2021 at "Annals of Oncology"
DOI: 10.1016/j.annonc.2021.01.013
Abstract: Thesis (Master)--Izmir Institute of Technology, Molecular Biology and Genetics, Izmir, 2019 read more here.
Keywords: effects multifunctional; multifunctional micelle; based nanocarriers; micelle based ... See more keywords
Biopolymer-based nanocarriers for sustained release of agrochemicals: A review on materials and social science perspectives for a sustainable future of agri- and horticulture.
Sign Up to like & getrecommendations! Published in 2022 at "Advances in colloid and interface science"
DOI: 10.1016/j.cis.2022.102645
Abstract: Devastating plant diseases and soil depletion rationalize an extensive use of agrochemicals to secure the food production worldwide. The sustained release of fertilizers and pesticides in agriculture is a promising solution to the eco-toxicological impacts… read more here.
Keywords: horticulture; sustained release; based nanocarriers; nanotechnology ... See more keywords
Synthesis of naringenin loaded lipid based nanocarriers and their in-vivo therapeutic potential in a rheumatoid arthritis model
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2021.102854
Abstract: Abstract Rheumatoid arthritis (RA) is a chronic inflammatory disease of joints with no permanent cure. Although, there are some treatment strategies for RA that can go into remission but a precise treatment strategy is not… read more here.
Keywords: lipid based; based nanocarriers; rheumatoid arthritis; loaded lipid ... See more keywords
Co1−XZnxFe2O4 based nanocarriers for dual-targeted anticancer drug delivery: Synthesis, characterization and in vivo and in vitro biocompatibility study
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2018.10.083
Abstract: Abstract The present paper aimed to synthesize, using thermal-treatment method, a variety of Co1-XZnxFe2O4-based nanocarriers (NCs) as Dual-controlled and targeted drug delivery systems (DDS) and provide a new structure as NCs suitable for the loading… read more here.
Keywords: xznxfe2o4 based; drug; based nanocarriers; drug delivery ... See more keywords
Improving the bioavailability of phenolic compounds by loading them within lipid-based nanocarriers
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DOI: 10.1016/j.tifs.2018.04.002
Abstract: Abstract Background Phenolic compounds1 are one of the main interested nutraceuticals in the food and pharmaceutical industries. The application of phenolics is limited due to their low bioavailability, low solubility, low stability, and un-targeted release.… read more here.
Keywords: lipid based; bioavailability; based nanocarriers; improving bioavailability ... See more keywords
Advances in Protein-Based Nanocarriers of Bioactive Compounds: From Microscopic Molecular Principles to Macroscopical Structural and Functional Attributes.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c01936
Abstract: Many proteins can be used to fabricate nanocarriers for encapsulation, protection, and controlled release of nutraceuticals. This review examined the protein-based nanocarriers from microscopic molecular characteristics to the macroscopical structural and functional attributes. Structural, physical,… read more here.
Keywords: macroscopical structural; microscopic molecular; protein based; functional attributes ... See more keywords
Exploration of Lipid-Based Nanocarriers as Drug Delivery Systems in Diabetic Foot Ulcer.
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DOI: 10.1021/acs.molpharmaceut.1c00970
Abstract: Diabetes mellitus is a chronic manifestation characterized by high levels of glucose in the blood resulting in several complications including diabetic wounds and ulcers, which predominantly require a longer duration of treatment and adversely affect… read more here.
Keywords: diabetic foot; delivery systems; foot ulcer; lipid based ... See more keywords