Strategies to load therapeutics into polysaccharide-based nanogels with a focus on microfluidics: A review.
Sign Up to like & getrecommendations! Published in 2021 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2021.118119
Abstract: Nowadays nanoparticles are increasingly investigated for the targeted and controlled delivery of therapeutics, as suggested by the high number of research articles (2400 in 2000 vs 8500 in 2020). Among them, almost 2% investigated nanogels… read more here.
Keywords: based nanogels; focus microfluidics; strategies load; load therapeutics ... See more keywords
Multi-color fluorescence of pNIPAM-Based nanogels modulated by dual stimuli-responsive FRET processes
Sign Up to like & getrecommendations! Published in 2017 at "Dyes and Pigments"
DOI: 10.1016/j.dyepig.2017.06.006
Abstract: Abstract We report the modulation of the dual photo/thermo-responsive multicolor fluorescence from poly( N -isopropyl acrylate) pNIPAM-based nanogels. The thermo-responsive pNIPAM-crosslinked matrix was covalently copolymerized with nitrobenzoxadiazole (NBD) monomers as a Forster resonance energy transfer… read more here.
Keywords: pnipam based; based nanogels; fluorescence; color fluorescence ... See more keywords
Tailoring Cellular Uptake and Fluorescence of Poly(2-oxazoline)-Based Nanogels.
Sign Up to like & getrecommendations! Published in 2017 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.7b00067
Abstract: Controlling the size and charge of nanometer-sized objects is of upmost importance for their interactions with cells. We herein present the synthesis of poly(2-oxazoline) based nanogels comprising a hydrophilic shell and an amine containing core… read more here.
Keywords: based nanogels; poly oxazoline; oxazoline based; cellular uptake ... See more keywords
Tumor targeting with pH-responsive poly(2-oxazoline)-based nanogels for metronomic doxorubicin treatment
Sign Up to like & getrecommendations! Published in 2018 at "Oncotarget"
DOI: 10.18632/oncotarget.24806
Abstract: The synthesis of a new nanogel drug carrier system loaded with the anti-cancer drug doxorubicin (DOX) is presented. Poly(2-oxazoline) (POx) based nanogels from block copolymer micelles were cross-linked and covalently loaded with DOX using pH-sensitive… read more here.
Keywords: based nanogels; microscopy; treatment; drug ... See more keywords
Development and Characterization of Cyclodextrin-Based Nanogels as a New Ibuprofen Cutaneous Delivery System
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14122567
Abstract: Nanogels combine the properties of hydrogels and nanocarrier systems, resulting in very effective drug delivery systems, including for cutaneous applications. Cyclodextrins (CDs) have been utilised to enhance the nanogels’ loading ability towards poorly soluble drugs… read more here.
Keywords: cutaneous delivery; based nanogels; release; formation ... See more keywords