Strategies to load therapeutics into polysaccharide-based nanogels with a focus on microfluidics: A review.
Sign Up to like & getrecommendations! Published in 2021 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2021.118119
Abstract: Nowadays nanoparticles are increasingly investigated for the targeted and controlled delivery of therapeutics, as suggested by the high number of research articles (2400 in 2000 vs 8500 in 2020). Among them, almost 2% investigated nanogels… read more here.
Keywords: based nanogels; focus microfluidics; strategies load; load therapeutics ... See more keywords
Multi-color fluorescence of pNIPAM-Based nanogels modulated by dual stimuli-responsive FRET processes
Sign Up to like & getrecommendations! Published in 2017 at "Dyes and Pigments"
DOI: 10.1016/j.dyepig.2017.06.006
Abstract: Abstract We report the modulation of the dual photo/thermo-responsive multicolor fluorescence from poly( N -isopropyl acrylate) pNIPAM-based nanogels. The thermo-responsive pNIPAM-crosslinked matrix was covalently copolymerized with nitrobenzoxadiazole (NBD) monomers as a Forster resonance energy transfer… read more here.
Keywords: pnipam based; based nanogels; fluorescence; color fluorescence ... See more keywords
Tailoring Cellular Uptake and Fluorescence of Poly(2-oxazoline)-Based Nanogels.
Sign Up to like & getrecommendations! Published in 2017 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.7b00067
Abstract: Controlling the size and charge of nanometer-sized objects is of upmost importance for their interactions with cells. We herein present the synthesis of poly(2-oxazoline) based nanogels comprising a hydrophilic shell and an amine containing core… read more here.
Keywords: based nanogels; poly oxazoline; oxazoline based; cellular uptake ... See more keywords
Impact of Protein Corona Formation on the Thermoresponsive Behavior of Acrylamide-Based Nanogels
Sign Up to like & getrecommendations! Published in 2024 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.3c01405
Abstract: The ability to fine-tune the volume phase transition temperature (VPTT) of thermoresponsive nanoparticles is essential to their successful application in drug delivery. The rational design of these materials is limited by our understanding of the… read more here.
Keywords: protein corona; based nanogels; acrylamide based; thermoresponsive behavior ... See more keywords
Cyclodextrin-Based Nanogels for Stabilization and Sensing of Curcumin
Sign Up to like & getrecommendations! Published in 2024 at "ACS Applied Nano Materials"
DOI: 10.1021/acsanm.4c02972
Abstract: Curcumin (CUR), a polyphenolic substance from turmeric, displays diverse medicinal properties. However, its instability poses challenges in detection. Cyclodextrin-based nanogels (CyDngs) offer a transformative solution, enhancing CUR’s stability in aqueous solutions. Multisensing approaches involving fluorescence,… read more here.
Keywords: sensing curcumin; cyclodextrin based; based nanogels; stabilization sensing ... See more keywords
Self-adjuvanted L-arginine-modified dextran-based nanogels for sustained local antigenic protein delivery to antigen-presenting cells and enhanced cellular and humoral immune responses.
Sign Up to like & getrecommendations! Published in 2024 at "Biomaterials science"
DOI: 10.1039/d3bm01150j
Abstract: In the development of cancer vaccines, antigens are delivered to elicit potent and specific T-cell responses to eradicate tumour cells. Nonetheless, successful vaccines are often hampered by the poor immunogenicity of tumour antigens, rapid clearance… read more here.
Keywords: antigen; based nanogels; presenting cells; cellular humoral ... See more keywords
Tumor targeting with pH-responsive poly(2-oxazoline)-based nanogels for metronomic doxorubicin treatment
Sign Up to like & getrecommendations! Published in 2018 at "Oncotarget"
DOI: 10.18632/oncotarget.24806
Abstract: The synthesis of a new nanogel drug carrier system loaded with the anti-cancer drug doxorubicin (DOX) is presented. Poly(2-oxazoline) (POx) based nanogels from block copolymer micelles were cross-linked and covalently loaded with DOX using pH-sensitive… read more here.
Keywords: based nanogels; microscopy; treatment; drug ... See more keywords
Development and Characterization of Cyclodextrin-Based Nanogels as a New Ibuprofen Cutaneous Delivery System
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14122567
Abstract: Nanogels combine the properties of hydrogels and nanocarrier systems, resulting in very effective drug delivery systems, including for cutaneous applications. Cyclodextrins (CDs) have been utilised to enhance the nanogels’ loading ability towards poorly soluble drugs… read more here.
Keywords: cutaneous delivery; based nanogels; release; formation ... See more keywords