The Effect of Cryoprotectants and Storage Conditions on the Transfection Efficiency, Stability and Safety of Lipid-Based Nanoparticles for mRNA and DNA Delivery.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202203022
Abstract: Lipid-based nanoparticles have recently shown great promise, establishing themselves as the gold standard in delivering novel RNA therapeutics. However, research on the effects of storage on their efficacy, safety and stability is still lacking. Here,… read more here.
Keywords: storage conditions; based nanoparticles; lipid based; stability ... See more keywords
Amorphous Copper-Based Nanoparticles with Clusterization-Triggered Phosphorescence for Ultrasensing 2,4,6-Trinitrotoluene.
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DOI: 10.1002/adma.202300526
Abstract: Amorphous metal-based nanostructures have attracted great attention recently due to their facilitative electron transfer and abundant reactive sites, whereas it remains enigmatic whether the amorphous copper-based nanoparticles (CuNPs) could be achieved. Here, for synthesizing amorphous… read more here.
Keywords: phosphorescence; clusterization triggered; amorphous copper; based nanoparticles ... See more keywords
Cytotoxicity of Metal‐Based Nanoparticles: From Mechanisms and Methods of Evaluation to Pathological Manifestations
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DOI: 10.1002/advs.202106049
Abstract: Metal‐based nanoparticles (NPs) are particularly important tools in tissue engineering‐, drug carrier‐, interventional therapy‐, and biobased technologies. However, their complex and varied migration and transformation pathways, as well as their continuous accumulation in closed biological… read more here.
Keywords: cytotoxicity metal; metal based; nanoparticles mechanisms; based nanoparticles ... See more keywords
Photosynthesis of hybrid silver-based nanoparticles mediated lectins and evaluation of their hemagglutinating properties.
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and applied biochemistry"
DOI: 10.1002/bab.2416
Abstract: Lectins are carbohydrate-binding proteins belonging to the Leguminosae family. In this family stand out proteins extracted from species belonging to Diocleinae subtribe, which includes, for example, the seed lectin from Dioclea violacea (DVL) and the… read more here.
Keywords: photosynthesis hybrid; silver; based nanoparticles; silver based ... See more keywords
Virus‐Based Nanoparticles of Simian Virus 40 in the Field of Nanobiotechnology
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DOI: 10.1002/biot.201700619
Abstract: Biomolecular nanostructures derived from living organisms, such as protein cages, fibers, and layers are drawing increasing interests as natural biomaterials. The virus‐based nanoparticles (VNPs) of simian virus 40 (SV40), with a cage‐like structure assembled from… read more here.
Keywords: based nanoparticles; virus based; field; nanobiotechnology ... See more keywords
Conjugated‐Polymer‐Based Nanoparticles with Efficient NIR‐II Fluorescent, Photoacoustic and Photothermal Performance
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DOI: 10.1002/cbic.201900309
Abstract: Fluorescence imaging (FI) and photoacoustic imaging (PA) play important roles in the real‐time assessment of cell‐based therapies. However, the limitations of conventional organic fluorescence contrast agents and the narrow range of the emission wavelength in… read more here.
Keywords: nanoparticles efficient; based nanoparticles; nir fluorescent; efficient nir ... See more keywords
Porphyrin-Based Nanoparticles: A Promising Phototherapy Platform.
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DOI: 10.1002/cplu.202200156
Abstract: Phototherapy, including photodynamic therapy and photothermal therapy, is an emerging form of non-invasive treatment. The combination of imaging technology and phototherapy is becoming an attractive development in the treatment of cancer, as it allows for… read more here.
Keywords: nanoparticles promising; promising phototherapy; based nanoparticles; phototherapy ... See more keywords
Self-Assembling PCL-Based Nanoparticles as PTX Solubility Enhancer Excipients.
Sign Up to like & getrecommendations! Published in 2018 at "Macromolecular bioscience"
DOI: 10.1002/mabi.201800164
Abstract: The advent of nanotechnology in medicine has allowed to eliminate the toxic excipients that are often necessary to formulate lipophilic drugs in clinics. An example is paclitaxel, one of the most important chemotherapeutic drugs developed… read more here.
Keywords: self assembling; based nanoparticles; pcl based; nanoparticles ptx ... See more keywords
Application and mechanisms of metal-based nanoparticles in the control of bacterial and fungal crop diseases.
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DOI: 10.1002/ps.7218
Abstract: Nanotechnology is a young branch of the discipline generated by nanomaterials. Its development has also greatly contributed to technological progress and product innovation in the field of agriculture. The antimicrobial properties of nanoparticles can be… read more here.
Keywords: crop diseases; bacterial fungal; metal based; based nanoparticles ... See more keywords
Spray-Dried Nanoparticle-in-Microparticle Delivery Systems (NiMDS) for Gene Delivery, Comprising Polyethylenimine (PEI)-Based Nanoparticles in a Poly(Vinyl Alcohol) Matrix.
Sign Up to like & getrecommendations! Published in 2018 at "Small"
DOI: 10.1002/smll.201701810
Abstract: Nucleic acid-based therapies rely on efficient formulations for nucleic acid protection and delivery. As nonviral strategies, polymeric and lipid-based nanoparticles have been introduced; however, biological efficacy and biocompatibility as well as poor storage properties due… read more here.
Keywords: polyethylenimine; based nanoparticles; delivery; nanoparticle microparticle ... See more keywords
Exploring the applications of hyaluronic acid‐based nanoparticles for diagnosis and treatment of bacterial infections
Sign Up to like & getrecommendations! Published in 2022 at "Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology"
DOI: 10.1002/wnan.1799
Abstract: Abstract Hyaluronic acid (HA) has become a topic of significant interest in drug delivery research due to its excellent properties, including biosafety, biodegradability, and nonimmunogenicity. Moreover, due to its ease of modification, HA can be… read more here.
Keywords: treatment bacterial; based nanoparticles; bacterial infections; hyaluronic acid ... See more keywords