The Effect of Cryoprotectants and Storage Conditions on the Transfection Efficiency, Stability and Safety of Lipid-Based Nanoparticles for mRNA and DNA Delivery.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202203022
Abstract: Lipid-based nanoparticles have recently shown great promise, establishing themselves as the gold standard in delivering novel RNA therapeutics. However, research on the effects of storage on their efficacy, safety and stability is still lacking. Here,… read more here.
Keywords: storage conditions; based nanoparticles; lipid based; stability ... See more keywords
Amorphous Copper-Based Nanoparticles with Clusterization-Triggered Phosphorescence for Ultrasensing 2,4,6-Trinitrotoluene.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced materials"
DOI: 10.1002/adma.202300526
Abstract: Amorphous metal-based nanostructures have attracted great attention recently due to their facilitative electron transfer and abundant reactive sites, whereas it remains enigmatic whether the amorphous copper-based nanoparticles (CuNPs) could be achieved. Here, for synthesizing amorphous… read more here.
Keywords: phosphorescence; clusterization triggered; amorphous copper; based nanoparticles ... See more keywords
Cytotoxicity of Metal‐Based Nanoparticles: From Mechanisms and Methods of Evaluation to Pathological Manifestations
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202106049
Abstract: Metal‐based nanoparticles (NPs) are particularly important tools in tissue engineering‐, drug carrier‐, interventional therapy‐, and biobased technologies. However, their complex and varied migration and transformation pathways, as well as their continuous accumulation in closed biological… read more here.
Keywords: cytotoxicity metal; metal based; nanoparticles mechanisms; based nanoparticles ... See more keywords
Photosynthesis of hybrid silver-based nanoparticles mediated lectins and evaluation of their hemagglutinating properties.
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and applied biochemistry"
DOI: 10.1002/bab.2416
Abstract: Lectins are carbohydrate-binding proteins belonging to the Leguminosae family. In this family stand out proteins extracted from species belonging to Diocleinae subtribe, which includes, for example, the seed lectin from Dioclea violacea (DVL) and the… read more here.
Keywords: photosynthesis hybrid; silver; based nanoparticles; silver based ... See more keywords
Virus‐Based Nanoparticles of Simian Virus 40 in the Field of Nanobiotechnology
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DOI: 10.1002/biot.201700619
Abstract: Biomolecular nanostructures derived from living organisms, such as protein cages, fibers, and layers are drawing increasing interests as natural biomaterials. The virus‐based nanoparticles (VNPs) of simian virus 40 (SV40), with a cage‐like structure assembled from… read more here.
Keywords: based nanoparticles; virus based; field; nanobiotechnology ... See more keywords
Conjugated‐Polymer‐Based Nanoparticles with Efficient NIR‐II Fluorescent, Photoacoustic and Photothermal Performance
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DOI: 10.1002/cbic.201900309
Abstract: Fluorescence imaging (FI) and photoacoustic imaging (PA) play important roles in the real‐time assessment of cell‐based therapies. However, the limitations of conventional organic fluorescence contrast agents and the narrow range of the emission wavelength in… read more here.
Keywords: nanoparticles efficient; based nanoparticles; nir fluorescent; efficient nir ... See more keywords
Polymer‐Based Nanoparticles for Inner Ear Targeted Trans Differentiation Gene Therapy
Sign Up to like & getrecommendations! Published in 2024 at "ChemMedChem"
DOI: 10.1002/cmdc.202400038
Abstract: Hearing loss is a significant disability that often goes under recognised, largely due to poor identification, prevention, and treatment. Steps are being made to amend these pitfalls in the investigation of hearing loss, however, the… read more here.
Keywords: based nanoparticles; loss; nanoparticles inner; hearing loss ... See more keywords
Enhancing WRAP‐Based Nanoparticles for Small Interfering Ribonucleic Acid Delivery in pH‐Sensitive Environments
Sign Up to like & getrecommendations! Published in 2025 at "Chemmedchem"
DOI: 10.1002/cmdc.202400885
Abstract: Small interfering RNAs (siRNA) are promising therapeutic molecules that require delivery systems to reach their targets. Several siRNA delivery systems, such as lipid‐ or peptide‐based nanoparticles, are developed for different pathologies. In this context, we… read more here.
Keywords: based nanoparticles; small interfering; delivery; wrap based ... See more keywords
Porphyrin-Based Nanoparticles: A Promising Phototherapy Platform.
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DOI: 10.1002/cplu.202200156
Abstract: Phototherapy, including photodynamic therapy and photothermal therapy, is an emerging form of non-invasive treatment. The combination of imaging technology and phototherapy is becoming an attractive development in the treatment of cancer, as it allows for… read more here.
Keywords: nanoparticles promising; promising phototherapy; based nanoparticles; phototherapy ... See more keywords
Designing Fe8-N2 Catalytic Sites of Nitrogen-Doped Iron-Based Nanoparticles with Oxidase-Like Activity: Characterization, Calculation and Application.
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DOI: 10.1002/cssc.202400252
Abstract: Designing metal nanoparticles with oxidase-mimicking capabilities has garnered significant attention due to their promising attributes. However, understanding the intricate catalytic mechanisms underlying these nanoparticles poses a formidable challenge. In this study, a straightforward pyrolysis procedure… read more here.
Keywords: based nanoparticles; nanoparticles oxidase; nitrogen doped; doped iron ... See more keywords
Self-Assembling PCL-Based Nanoparticles as PTX Solubility Enhancer Excipients.
Sign Up to like & getrecommendations! Published in 2018 at "Macromolecular bioscience"
DOI: 10.1002/mabi.201800164
Abstract: The advent of nanotechnology in medicine has allowed to eliminate the toxic excipients that are often necessary to formulate lipophilic drugs in clinics. An example is paclitaxel, one of the most important chemotherapeutic drugs developed… read more here.
Keywords: self assembling; based nanoparticles; pcl based; nanoparticles ptx ... See more keywords