Clinical implications of tumor‐based next‐generation sequencing in high‐grade epithelial ovarian cancer
Sign Up to like & getrecommendations! Published in 2023 at "Cancer"
DOI: 10.1002/cncr.34724
Abstract: Tumor‐based next‐generation sequencing is used inconsistently as a tool to tailor treatment of ovarian cancer, yet beyond detection of somatic BRCA1 and BRCA2 mutations, the clinical benefit is not well established. This study aimed to… read more here.
Keywords: tumor based; based next; ovarian cancer; next generation ... See more keywords
Development of microsatellite markers for Myracrodruon urundeuva (F.F. & M.F. Allemão), a highly endangered species from tropical forest based on next-generation sequencing
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Biology Reports"
DOI: 10.1007/s11033-017-4142-z
Abstract: Myracrodruon urundeuva is a tree species of high economic importance due the strength and durability of its wood. Threatened of extinction in Brazil, it is present only in a few forest remnants, mostly in conservation… read more here.
Keywords: myracrodruon urundeuva; based next; development microsatellite; next generation ... See more keywords
74 Analysis of chromosomal abnormality of bovine IVF embryos based on next-generation sequencing
Sign Up to like & getrecommendations! Published in 2020 at "Reproduction, Fertility and Development"
DOI: 10.1071/rdv32n2ab74
Abstract: It has been suggested that bovine IVF embryos have a higher frequency of occurrence of chromosomal abnormalities than in vivo-fertilised embryos, which may explain low pregnancy success, but the details have not been clarified (Yao et… read more here.
Keywords: ivf embryos; bovine ivf; based next; embryos ... See more keywords
Potential pitfalls in multiplex PCR-based next-generation sequencing: a case-based report
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Pathology"
DOI: 10.1136/jclinpath-2021-208105
Abstract: Amplicon-based next-generation sequencing (NGS) assays employ highly sensitive, rapid, and cost-effective methods to detect clinically actionable mutations for the diagnosis, prognosis, and treatment of patients with cancer. However, recognition of certain limitations inherent to amplicon-based… read more here.
Keywords: based next; report; next generation; potential pitfalls ... See more keywords
Blood-based next-generation sequencing analysis of neuroendocrine tumors.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.15_suppl.4110
Abstract: 4110 Background: Neuroendocrine tumors (NET) comprise around 2% of all malignant tumors of the gastrointestinal system. The genomic landscape of NET has not been well studied. The aim of this study was to confirm the… read more here.
Keywords: based next; generation sequencing; next generation; blood based ... See more keywords
Identification of MET Exon 14 skipping by targeted RNA-based next-generation sequencing in Chinese Patients with NSCLC.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.15_suppl.e20018
Abstract: e20018 Background: MET (mesenchymal-epithelial transition) exon14 skipping mutations have been reported to represent a clinically unique molecular subtype of NSCLC. The prevalence rates of MET exon 14 skipping in lung adenocarcinoma are quite different, from… read more here.
Keywords: met exon; based next; nsclc patients; next generation ... See more keywords
Multiplex PCR−Based Next-Generation Sequencing and Global Diversity of Seoul Virus in Humans and Rats
Sign Up to like & getrecommendations! Published in 2018 at "Emerging Infectious Diseases"
DOI: 10.3201/eid2402.171216
Abstract: Seoul virus (SEOV) poses a worldwide public health threat. This virus, which is harbored by Rattus norvegicus and R. rattus rats, is the causative agent of hemorrhagic fever with renal syndrome (HFRS) in humans, which… read more here.
Keywords: seoul virus; based next; multiplex pcr; next generation ... See more keywords
Corrigendum: Amplicon-Based, Next-Generation Sequencing Approaches to Characterize Single Nucleotide Polymorphisms of Orthohantavirus Species
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2021.804914
Abstract: [This corrects the article DOI: 10.3389/fcimb.2020.565591.]. read more here.
Keywords: sequencing approaches; next generation; based next; corrigendum amplicon ... See more keywords
A Novel Algorithm for Detecting Microsatellite Instability Based on Next-Generation Sequencing Data
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.916379
Abstract: Objectives Microsatellite instability (MSI) is the condition of genetic hypermutability caused by spontaneous acquisition or loss of nucleotides during the DNA replication. MSI has been discovered to be a useful immunotherapy biomarker clinically. The main… read more here.
Keywords: based next; microsatellite instability; next generation; msi ... See more keywords