Evodiamine-Based Nitroreductase Responsive Theranostic Agents for Treatment of Colon Cancer.
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DOI: 10.1021/acs.jmedchem.4c02822
Abstract: Hypoxia is a state of low oxygen tension that is found in numerous solid tumors. Generally, nitroreductase (NTR) is overexpressed and directly correlated with the hypoxic status in solid tumors, supporting the hypothesis that prodrug… read more here.
Keywords: evodiamine; treatment; based nitroreductase; evodiamine based ... See more keywords