Prognostic Implication of Inflammation-based Prognostic Scores in Patients with Intrahepatic Cholangiocarcinoma Treated with First-line Gemcitabine plus Cisplatin
Sign Up to like & getrecommendations! Published in 2017 at "Investigational New Drugs"
DOI: 10.1007/s10637-017-0548-7
Abstract: SummaryBackground We aimed to comprehensively evaluate the prognostic value of inflammation-based prognostic scores, including the modified Glasgow Prognostic Score (mGPS), neutrophil–lymphocyte ratio (NLR), and platelet–lymphocyte ratio (PLR), exclusively in patients with advanced intrahepatic cholangiocarcinoma (iCCA).… read more here.
Keywords: prognostic scores; first line; based prognostic; inflammation based ... See more keywords
Identification of survival-related genes and a novel gene-based prognostic signature involving the tumor microenvironment of uveal melanoma.
Sign Up to like & getrecommendations! Published in 2021 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2021.107816
Abstract: Uveal melanoma (UM) is the most common primary intraocular malignant tumor in adults and almost fifty percent of patients subsequently develop systemic metastases usually involving the liver. The tumor microenvironment (TME) is crucial to the… read more here.
Keywords: prognostic signature; based prognostic; gene based; gene ... See more keywords
P215 Blood-based prognostic biomarkers in Crohn’s patients treated with biologics: a new promising tool to predict endoscopic outcomes
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DOI: 10.1093/ecco-jcc/jjab076.341
Abstract: There is a growing need for biomarkers of inflammation to monitor and predict therapeutic outcome in Crohn’s disease (CD) patients. We aimed to evaluate whether the level of circulating blood cells, expressed as ratios (NLR,… read more here.
Keywords: blood; elr enlr; predict endoscopic; based prognostic ... See more keywords
MP09-01 GENOMIC HETEROGENEITY IN TISSUE-BASED PROGNOSTIC SIGNATURES FROM PROSTATE BIOPSIES; RESULTS FROM TWO PROSPECTIVE TRIALS
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Urology"
DOI: 10.1097/ju.0000000000000829.01
Abstract: INTRODUCTION AND OBJECTIVE: Tissue based prognostic signatures have been used in various stages of prostate cancer, including biopsy tissue from men who are deciding between active surveillance versus treatment. Recent studies have suggested that these… read more here.
Keywords: tissue based; prognostic signatures; prospective trials; tissue ... See more keywords
An Adaptive Maintenance Policy With Nonlinear Degradation Modeling Based on Prognostic Information
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DOI: 10.1109/access.2020.3020375
Abstract: Prognostics and health management (PHM) technology is an extremely important research focus in the field of reliability engineering. The ultimate goal of applying PHM technology is health management. Aiming at nonlinear degradation systems, an adaptive… read more here.
Keywords: adaptive maintenance; maintenance policy; degradation; prognostic information ... See more keywords
Integrated Analysis Identifies an Immune-Based Prognostic Signature for the Mesenchymal Identity in Gastric Cancer
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DOI: 10.1155/2020/9780981
Abstract: Background Gastric cancer (GC) has been divided into four molecular subtypes, of which the mesenchymal subtype has the poorest survival. Our goal is to develop a prognostic signature by integrating the immune system and molecular… read more here.
Keywords: prognostic signature; gastric cancer; analysis; based prognostic ... See more keywords
Comprehensive molecular profiling of multi-focal prostate cancer and concomitant lymph node metastasis: Implications for tissue-based prognostic biomarkers.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.5061
Abstract: 5061Background: Current tissue-based prognostic biomarker assays claim that assessment of a single biopsy focus is sufficient to predict disease behavior. We analyzed and compared the genetic profi... read more here.
Keywords: tissue based; multi focal; comprehensive molecular; profiling multi ... See more keywords
The impact of a web-based prognostic intervention on physicians’ prognostic confidence.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2021.39.15_suppl.12106
Abstract: 12106 Background: Clinicians often hesitate to discuss prognosis with patients because of prognostic uncertainty. The use of validated prognostic models may enhance prognostic confidence and/or prognostic accuracy. Prognostic confidence is a novel concept that has… read more here.
Keywords: prognostic confidence; prognosis; intervention; confidence ... See more keywords
A Tumor Suppressor Gene-Based Prognostic Classifier Predicts Prognosis, Tumor Immune Infiltration, and Small Molecule Compounds in Breast Cancer
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DOI: 10.3389/fgene.2021.783026
Abstract: Objective: Tumor suppressor genes (TSGs) play critical roles in the cell cycle checkpoints and in modulating genomic stability. Here, we aimed to develop a TSG-based prognostic classifier for breast cancer. Methods: Gene expression profiles and… read more here.
Keywords: small molecule; based prognostic; prognostic classifier; breast cancer ... See more keywords
Screening to Identify an Immune Landscape-Based Prognostic Predictor and Therapeutic Target for Prostate Cancer
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DOI: 10.3389/fonc.2021.761643
Abstract: Objectives Existing prognostic risk assessment strategies for prostate cancer (PCa) remain unsatisfactory. Similar treatments for patients at the same disease stage can lead to different survival outcomes. Thus, we aimed to explore a novel immune… read more here.
Keywords: prognostic predictor; predictor therapeutic; based prognostic; landscape based ... See more keywords
NEUROD1 predicts better prognosis in pancreatic cancer revealed by a TILs-based prognostic signature
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.1025921
Abstract: It has been well-defined that tumor-infiltrating lymphocytes (TILs) play critical roles in pancreatic cancer (PaCa) progression. This research aimed to comprehensively explore the composition of TILs in PaCa and their potential clinical significance. A total… read more here.
Keywords: paca; pancreatic cancer; signature; based prognostic ... See more keywords