Articles with "based proteomics" as a keyword



Blood‐Based Proteomics for Adult‐Onset Focal Dystonias

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Published in 2024 at "Annals of Neurology"

DOI: 10.1002/ana.26929

Abstract: The adult‐onset focal dystonias are characterized by over‐active muscles leading to abnormal movements. For most cases, the etiology and pathogenesis remain unknown. In the current study, unbiased proteomics methods were used to identify potential changes… read more here.

Keywords: based proteomics; proteomics adult; blood based; focal dystonias ... See more keywords

Mass Spectrometry-Based Proteomics.

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Published in 2018 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-7804-5_9

Abstract: Proteomics is the large-scale analysis of proteins rendered possible by modern mass spectrometry analysis methods capable of identifying thousands of peptides/proteins in a fast high-throughput manner. Here I describe protocols for the preparation of fungal… read more here.

Keywords: spectrometry; mass spectrometry; analysis; based proteomics ... See more keywords
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A Roadmap to Domain Based Proteomics.

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Published in 2019 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-8736-8_16

Abstract: Protein domains are reusable segments of proteins and play an important role in protein evolution. By combining the elements from a relatively small set of domains into unique arrangements, a large number of distinct proteins can… read more here.

Keywords: protein; based proteomics; biology; roadmap domain ... See more keywords
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Application of an Aptamer-Based Proteomics Assay (SOMAscan™) in Rat Cerebrospinal Fluid.

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Published in 2019 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-9706-0_13

Abstract: The exploration of the cerebrospinal fluid (CSF) through proteomics techniques might help in the search of molecular biomarkers relevant to neurological pathologies. Aiming this, we describe here a commercially available multiplexed proteomics technology based on… read more here.

Keywords: aptamer based; based proteomics; application aptamer; rat ... See more keywords

Combinatorial Electrophoresis and Mass Spectrometry-Based Proteomics in Breast Milk for Breast Cancer Biomarker Discovery.

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Published in 2019 at "Advances in experimental medicine and biology"

DOI: 10.1007/978-3-030-15950-4_26

Abstract: Innovations in approaches for early detection and individual risk assessment of different cancers, including breast cancer (BC), are needed to reduce cancer morbidity and associated mortality. The assessment of potential cancer biomarkers in accessible bodily… read more here.

Keywords: milk; mass spectrometry; based proteomics; breast cancer ... See more keywords
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Liquid chromatography mass spectrometry-based proteomics of Escherichia coli single colony

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Published in 2021 at "MethodsX"

DOI: 10.1016/j.mex.2021.101277

Abstract: The Escherichia coli proteome is the most extensively characterized and studied of all prokaryotic proteomes. Despite this, large scale bacterial proteomics experiments performed on E. coli cells grown in liquid cultures have failed to identify… read more here.

Keywords: colony; mass spectrometry; escherichia coli; based proteomics ... See more keywords

Biodegradation of Punicalagin into Ellagic Acid by Selected Probiotic Bacteria: A Study of the Underlying Mechanisms by MS-Based Proteomics

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Published in 2022 at "Journal of Agricultural and Food Chemistry"

DOI: 10.1021/acs.jafc.2c06585

Abstract: Pomegranate (Punica granatum L.) is a well-known source of bioactive phenolic compounds such as ellagitannins, anthocyanins, and flavanols. Punicalagin, one of the main constituents of pomegranate, needs to be biodegraded by bacteria to yield metabolites… read more here.

Keywords: punicalagin ellagic; biodegradation punicalagin; based proteomics; ellagic acid ... See more keywords

Mass spectrometry-based proteomics data from thousands of HeLa control samples

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Published in 2024 at "Scientific Data"

DOI: 10.1038/s41597-024-02922-z

Abstract: Here we provide a curated, large scale, label free mass spectrometry-based proteomics data set derived from HeLa cell lines for general purpose machine learning and analysis. Data access and filtering is a tedious task, which… read more here.

Keywords: proteomics data; based proteomics; mass spectrometry; spectrometry based ... See more keywords

Evaluation and optimization of reduction and alkylation methods to maximize peptide identification with MS-based proteomics.

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Published in 2017 at "Molecular bioSystems"

DOI: 10.1039/c7mb00393e

Abstract: Mass spectrometry (MS) has become an increasingly important technique to analyze proteins. In popular bottom-up MS-based proteomics, reduction and alkylation are routine steps to facilitate peptide identification. However, incomplete reactions and side reactions may occur,… read more here.

Keywords: reduction; based proteomics; reduction alkylation; alkylation ... See more keywords

The PRIDE database resources in 2022: a hub for mass spectrometry-based proteomics evidences.

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Published in 2021 at "Nucleic acids research"

DOI: 10.1093/nar/gkab1038

Abstract: The PRoteomics IDEntifications (PRIDE) database (https://www.ebi.ac.uk/pride/) is the world's largest data repository of mass spectrometry-based proteomics data. PRIDE is one of the founding members of the global ProteomeXchange (PX) consortium and an ELIXIR core data… read more here.

Keywords: pride; mass spectrometry; pride database; mass ... See more keywords

Based on proteomics to explore the mechanism of mecobalamin promoting the repair of injured peripheral nerves.

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Published in 2022 at "Canadian journal of physiology and pharmacology"

DOI: 10.1139/cjpp-2021-0692

Abstract: Mecobalamin is commonly used in the adjuvant intervention of various peripheral nerve injuries. Actin cytoskeleton plays a role in regeneration of myelin and axon. Therefore, the purpose of this study was to explore the possibility… read more here.

Keywords: actin cytoskeleton; based proteomics; group; proteomics explore ... See more keywords