Relative Effectiveness of Cell-Based Versus Egg-Based Quadrivalent Influenza Vaccines in Adults During the 2019–2020 Influenza Season in the United States
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DOI: 10.1093/ofid/ofac532
Abstract: Abstract Background Mutations occurring during egg-based influenza vaccine production may affect vaccine effectiveness. The mammalian cell-based quadrivalent inactivated influenza vaccine (IIV4c) demonstrated improved protection relative to egg-based vaccines in prior seasons. This study estimated the… read more here.
Keywords: 2020 influenza; based quadrivalent; influenza; egg based ... See more keywords
Modelling the Economic Impact of lnfluenza Vaccine Programs with the Cell-Based Quadrivalent Influenza Vaccine and Adjuvanted Trivalent Influenza Vaccine in Canada
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DOI: 10.3390/vaccines10081257
Abstract: In Canada, approximately 12,000 people annually are hospitalized with influenza. While vaccination is the most effective method for reducing the burden of seasonal influenza, the propagation of vaccine virus strains in eggs can result in… read more here.
Keywords: cell based; based quadrivalent; influenza vaccine; adjuvanted trivalent ... See more keywords
The Epidemiological and Economic Impact of a Cell-Based Quadrivalent Influenza Vaccine in Adults in the US: A Dynamic Modeling Approach
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DOI: 10.3390/vaccines9101095
Abstract: Mutations of the H3N2 vaccine strain during the egg-based vaccine manufacturing process partly explain the suboptimal effectiveness of traditional seasonal influenza vaccines. Cell-based influenza vaccines improve antigenic match and vaccine effectiveness by avoiding such egg-adaptation.… read more here.
Keywords: influenza vaccine; quadrivalent influenza; impact; cell based ... See more keywords