DNTT activation, TdT‐aided gene length mutation, and better prognosis in ATG‐based regimen allo‐HSCT in AML
Sign Up to like & getrecommendations! Published in 2023 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23514
Abstract: This study aimed to investigate the relationship between anomalous DNA nucleotidylexotransferase (DNTT) activation and the mutagenesis of gene length mutations (LMs) in acute myeloid leukemia (AML), and the relevance of their prognosis in antithymocyte globulin… read more here.
Keywords: regimen allo; aml; dntt activation; based regimen ... See more keywords
Salvage therapy post pomalidomide-based regimen in relapsed/refractory myeloma
Sign Up to like & getrecommendations! Published in 2018 at "Annals of Hematology"
DOI: 10.1007/s00277-018-3236-6
Abstract: The combination of pomalidomide and low-dose dexamethasone (Pom-Dex) has proved effective and safe in patients with end-stage relapsed/refractory multiple myeloma (RRMM), otherwise characterized by a very poor outcome. MM remains an incurable disease with unavoidable… read more here.
Keywords: relapsed refractory; based regimen; pom dex; therapy ... See more keywords
Adjuvant concurrent chemoradiotherapy with low-dose daily cisplatin for extrahepatic bile duct cancer
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-017-3312-y
Abstract: PurposeWe aimed to present the clinical outcomes of adjuvant concurrent chemoradiotherapy (CCRT) with low-dose daily cisplatin regimen compared to the conventional 5-fluorouracil (5-FU)-based regimen for extrahepatic bile duct cancer (EHBDC).MethodsFrom October 1994 to April 2013,… read more here.
Keywords: low dose; dose daily; daily cisplatin; ccrt ... See more keywords
Starting or Switching to an Integrase Inhibitor-Based Regimen Affects PTSD Symptoms in Women with HIV
Sign Up to like & getrecommendations! Published in 2020 at "AIDS and Behavior"
DOI: 10.1007/s10461-020-02967-2
Abstract: As the use of Integrase inhibitor (INSTI)-class antiretroviral medications becomes more common to maintain long-term viral suppression, early reports suggest the potential for CNS side-effects when starting or switching to an INSTI-based regimen. In a… read more here.
Keywords: starting switching; ptsd symptoms; integrase inhibitor; subscale ... See more keywords
Ceftazidime-Avibactam-Based Versus Tigecycline-Based Regimen for the Treatment of Carbapenem-Resistant Klebsiella pneumoniae-Induced Pneumonia in Critically Ill Patients.
Sign Up to like & getrecommendations! Published in 2021 at "Infectious diseases and therapy"
DOI: 10.1007/s40121-021-00542-3
Abstract: Introduction The aim of the present study was to assess the safety profile and outcomes of a ceftazidime-avibactam (CAZ-AVI)-based regimen and compare them with those of a tigecycline (TGC)-based regimen in intensive care unit (ICU)… read more here.
Keywords: caz avi; treatment; group; critically ill ... See more keywords
Cost-Utility Analysis of a Dolutegravir-Based Versus Low-Dose Efavirenz-Based Regimen for the Initial Treatment of HIV-Infected Patients in Cameroon (NAMSAL ANRS 12313 Trial)
Sign Up to like & getrecommendations! Published in 2020 at "PharmacoEconomics"
DOI: 10.1007/s40273-020-00987-3
Abstract: Evidence comparing the economic and patient values of the World Health Organization’s preferred (dolutegravir 50 mg [DTG]-based) and alternative (low-dose [400 mg] efavirenz [EFV400]-based) first-line antiretroviral regimens is limited. We compared patient-reported outcomes (PROs), costs,… read more here.
Keywords: trial; dtg based; utility; analysis ... See more keywords
Comparative Studies on the Efficacy and Safety of Ainuovirine-Based Versus Efavirenz-Based Antiretroviral Therapy in the Management of Persons Living with HIV: A Real-World Study in Guizhou, China
Sign Up to like & getrecommendations! Published in 2024 at "AIDS Research and Human Retroviruses"
DOI: 10.1089/aid.2024.0030
Abstract: In China, non-nucleoside reverse transcriptase inhibitors (NNRTIs) are integral to the antiretroviral therapy (ART) regimen for persons living with HIV (PWH), comprising over 80% of such treatments. To broaden treatment options and improve therapeutic effectiveness,… read more here.
Keywords: antiretroviral therapy; living hiv; therapy; based regimen ... See more keywords
Optimizing Treatment for Human Immunodeficiency Virus to Improve Clinical Outcomes Using Precision Medicine.
Sign Up to like & getrecommendations! Published in 2023 at "American journal of epidemiology"
DOI: 10.1093/aje/kwad057
Abstract: In first-line antiretroviral therapy (ART) for human immunodeficiency virus (HIV) treatment, some subgroups of patients may respond better to an efavirenz (EFV)-based regimen compared to an integrase strand transfer inhibitor (InSTI)-based regimen, or vice versa,… read more here.
Keywords: medicine; immunodeficiency virus; based regimen; precision medicine ... See more keywords
#2334 Rituximab based regimen is safe and effective for primary membranous nephropathy patients presented with nephrotic syndrome and advanced renal dysfunction
Sign Up to like & getrecommendations! Published in 2025 at "Nephrology Dialysis Transplantation"
DOI: 10.1093/ndt/gfaf116.1209
Abstract: The immunosuppressive therapy is often limited for the idiopathic membranous nephropathy (IMN) patients with advanced renal dysfunction due to potential increased risks. This study compared the efficacy and safety of the rituximab-based regimen (RTX) and… read more here.
Keywords: rituximab based; based regimen; group; advanced renal ... See more keywords
Incidence of Metabolic syndrome in people with HIV without experienCe to antiretroviral Therapy who start doLutegravir based-regimen compared with bictegrAvir based-regimeN after 48 weeks (MICTLAN trial).
Sign Up to like & getrecommendations! Published in 2025 at "AIDS"
DOI: 10.1097/qad.0000000000004259
Abstract: OBJECTIVE Evidence suggests that patients initiating a second-generation INSTI-based regimen may have a higher risk of developing metabolic syndrome (MetS) compared to those on other antiretroviral classes. This study aimed to describe the incidence of… read more here.
Keywords: bic taf; dtg abc; based regimen; incidence ... See more keywords
Resolution of Neuropsychiatric Adverse Events After Switching to a Doravirine-Based Regimen in the Open-Label Extensions of the DRIVE-AHEAD and DRIVE-FORWARD Trials.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of acquired immune deficiency syndromes"
DOI: 10.1097/qai.0000000000003599
Abstract: BACKGROUND Neuropsychiatric adverse events (NPAEs) are associated with several antiretrovirals. Doravirine (DOR), a non-nucleoside reverse transcriptase inhibitor indicated for HIV-1 treatment, does not interact significantly with known neurotransmitter receptors in vitro. First-line therapy with DOR-based… read more here.
Keywords: week; dor; based regimen; dor based ... See more keywords