Utilization of novel systemic therapies for multiple myeloma: A retrospective study of front‐line regimens using the SEER‐Medicare data
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Medicine"
DOI: 10.1002/cam4.2698
Abstract: The landscape of treatment for multiple myeloma (MM) has significantly changed over the last decade due to novel agents that have shown superiority in efficacy such as proteasome inhibitors (PIs) and immunomodulatory drugs (IMiDs) over… read more here.
Keywords: systemic therapies; utilization; medicare data; seer medicare ... See more keywords
Anthracycline Use for Early Stage Breast Cancer in the Modern Era: a Review
Sign Up to like & getrecommendations! Published in 2018 at "Current Treatment Options in Oncology"
DOI: 10.1007/s11864-018-0547-8
Abstract: Opinion statementAnthracycline-based regimens have been an important treatment component for patients with breast cancer. As demonstrated in the last Early Breast Cancer Trialists’ Collaborative Group (EBCTCG) meta-analysis, anthracycline-based regimens decrease breast cancer mortality by 20–30%.… read more here.
Keywords: risk; anthracycline; breast cancer; cancer ... See more keywords
Capecitabine Versus Continuous Infusion Fluorouracil for the Treatment of Advanced or Metastatic Colorectal Cancer: a Meta-analysis
Sign Up to like & getrecommendations! Published in 2018 at "Current Treatment Options in Oncology"
DOI: 10.1007/s11864-018-0597-y
Abstract: Opinion statementNowadays, systemic chemotherapy with intravenous (IV) 5-fluorouracil (5-FU) remains the most commonly prescribed treatment for metastatic colorectal cancers (CRC), in combination with other cytotoxic drugs. 5-FU can be administered through a bolus injection or… read more here.
Keywords: metastatic colorectal; continuous infusion; treatment; capecitabine ... See more keywords
Real-world safety and supportive care use of second-line 5-fluorouracil-based regimens among patients with metastatic pancreatic ductal adenocarcinoma.
Sign Up to like & getrecommendations! Published in 2022 at "Current medical research and opinion"
DOI: 10.1080/03007995.2022.2059976
Abstract: Objective Chemotherapy-related adverse events (AEs) can negatively impact the care of patients. The prevention and management of AEs often require additional medications. We evaluated the percentages of patients with metastatic pancreatic ductal adenocarcinoma (mPDAC) undergoing… read more here.
Keywords: second line; based regimens; patients treated; liposomal irinotecan ... See more keywords
Patient and treatment pathways for toxoplasmosis in the United States: data analysis of the Vizient Health Systems Data from 2011 to 2017
Sign Up to like & getrecommendations! Published in 2018 at "Pathogens and Global Health"
DOI: 10.1080/20477724.2018.1552644
Abstract: ABSTRACT Toxoplasmosis causes substantial morbidity and mortality in the United States (US). Clinical manifestations to toxoplasmosis vary and there is limited information on incidence or treatment patterns in the US. Treatment pathways for pyrimethamine-based regimens… read more here.
Keywords: treatment; toxoplasmosis; based regimens; tmp smx ... See more keywords
Etravirine and Rilpivirine Drug Resistance Among HIV-1 Subtype C Infected Children Failing Non-Nucleoside Reverse Transcriptase Inhibitor-Based Regimens in South India.
Sign Up to like & getrecommendations! Published in 2017 at "AIDS research and human retroviruses"
DOI: 10.1089/aid.2016.0133
Abstract: We have analyzed reverse transcriptase (RT) region of HIV-1 pol gene from 97 HIV-infected children who were identified as failing first-line therapy that included first-generation non-nucleoside RT inhibitors (Nevirapine and Efavirenz) for at least 6… read more here.
Keywords: based regimens; non nucleoside; resistance; reverse transcriptase ... See more keywords
Efficacy and safety of Doravirine-based regimens in real life: a prospective, monocentric, French study.
Sign Up to like & getrecommendations! Published in 2022 at "AIDS research and human retroviruses"
DOI: 10.1089/aid.2022.0058
Abstract: Doravirine (DOR) efficacy and safety has been evaluated in adult naïve or treated patients starting a DOR-based regimen between 09/15/2019 and 12/31/2020. Medical history and examination, laboratory results, tolerance were assessed during the 48 weeks… read more here.
Keywords: efficacy safety; dor; based regimens; doravirine ... See more keywords
Efficacy and toxicity of carfilzomib- or bortezomib-based regimens for treatment of transplant-ineligible patients with newly diagnosed multiple myeloma: A meta-analysis
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DOI: 10.1097/md.0000000000030715
Abstract: Background: Multiple myeloma is a clonal disorder of malignant plasma cells that comprises approximately 10% of hematologic malignancies. The aim of this study was to investigate the efficacy and toxicity of carfilzomib- or bortezomib-based regimens… read more here.
Keywords: based regimens; ineligible patients; transplant ineligible; bortezomib based ... See more keywords
Challenges of scale-up to Dolutegravir based regimens in sub-Saharan Africa: a case study in Togo.
Sign Up to like & getrecommendations! Published in 2019 at "AIDS"
DOI: 10.1097/qad.0000000000002470
Abstract: OBJECTIVE Evaluate the potential effectiveness of the implementation of DTG-based regimens in patients on failing current ART given the high levels of NRTI resistance in Togo. DESIGN Patients on ART attending health facilities for routine… read more here.
Keywords: saharan africa; dtg based; based regimens; togo ... See more keywords
Translational Approach to Predicting the Efficacy of Maraviroc-Based Regimens as HIV Preexposure Prophylaxis
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DOI: 10.1128/aac.01729-19
Abstract: Maraviroc-based regimens have been explored as preexposure prophylaxis (PrEP) against human immunodeficiency virus (HIV). In this study, we utilized mucosal tissue drug exposure data, combined with target concentrations generated in vitro, in a pharmacokinetic-pharmacodynamic analysis… read more here.
Keywords: efficacy; based regimens; maraviroc based; preexposure prophylaxis ... See more keywords
Perioperative Sedation in Mechanically Ventilated Cardiac Surgery Patients With Dexmedetomidine-Based Versus Propofol-Based Regimens
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DOI: 10.1177/1060028018793254
Abstract: Background: Sedative agents used during cardiac surgery can influence the patient’s time to extubation, intensive care unit (ICU) and hospital length of stay, and incidence of delirium. Objective: This study evaluates the effects of the… read more here.
Keywords: surgery; propofol; extubation; cardiac surgery ... See more keywords