Based on RNA-Seq analysis identification and expression analysis of Trans-scripusinA synthesize-related genes of UV-treatment in postharvest grape fruit.
Sign Up to like & getrecommendations! Published in 2020 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2020.108471
Abstract: Stilbenes, an active substances closely related to resistance and quality of grapes, are rarely found in natural resources. However its cumulative amount is affected by ultraviolet radiation (UV). The purpose of this study is to… read more here.
Keywords: grape; based rna; analysis; sah genes ... See more keywords
Clinical progress of nanomedicine-based RNA therapies
Sign Up to like & getrecommendations! Published in 2021 at "Bioactive Materials"
DOI: 10.1016/j.bioactmat.2021.10.018
Abstract: The clinical application of nanoparticles (NPs) to deliver RNA for therapy has progressed rapidly since the FDA approval of Onpattro® in 2018 for the treatment of polyneuropathy associated with hereditary transthyretin amyloidosis. The emergency use… read more here.
Keywords: based rna; rna; progress nanomedicine; clinical progress ... See more keywords
Microfluidic technologies and devices for lipid nanoparticle-based RNA delivery
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Controlled Release"
DOI: 10.1016/j.jconrel.2022.02.017
Abstract: In 2021, mRNA vaccines against COVID-19 were approved by the Food and Drug Administration. mRNA vaccines are important for preventing severe COVID-19 and returning to normal life. The development of RNA-delivery technology, including mRNA vaccines,… read more here.
Keywords: mrna vaccines; rna delivery; rna loaded; production ... See more keywords
Identification of miRNomes associated with adult neurogenesis after stroke using Argonaute 2-based RNA sequencing
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DOI: 10.1080/15476286.2016.1196320
Abstract: ABSTRACT Neurogenesis is associated with functional recovery after stroke. However, the underlying molecular mechanisms have not been fully investigated. Using an Ago2-based RNA immunoprecipitation to immunoprecipated Ago2-RNA complexes followed by RNA sequencing (Ago2 RIP-seq) approach,… read more here.
Keywords: non ischemic; rna sequencing; adult neurogenesis; based rna ... See more keywords
VeTra: a tool for trajectory inference based on RNA velocity
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DOI: 10.1093/bioinformatics/btab364
Abstract: Abstract Motivation Trajectory inference (TI) for single cell RNA sequencing (scRNAseq) data is a powerful approach to interpret dynamic cellular processes such as cell cycle and development. Still, however, accurate inference of trajectory is challenging.… read more here.
Keywords: rna velocity; trajectory; based rna; trajectory inference ... See more keywords
Predicting Treatment Response Based on RNA Expression in Large Datasets
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Cancer Research"
DOI: 10.1158/1078-0432.ccr-18-2823
Abstract: PD-L1 expression levels derived from >16,000 samples guided the selection of tumor types likely to benefit from pembrolizuamb monotherapy in clinical trials. Although not fail-proof, FDA approvals for most of the prioritized indications speak to… read more here.
Keywords: based rna; treatment response; predicting treatment; expression ... See more keywords
Fluorescent nucleic acid probe in droplets for bacterial sorting (FNAP-sort) as a high-throughput screening method for environmental bacteria with various growth rates
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DOI: 10.1371/journal.pone.0214533
Abstract: We have developed a new method for selectively sorting droplets containing growing bacteria using a fluorescence resonance energy transfer (FRET)-based RNA probe. Bacteria and the FRET-based RNA probe are encapsulated into nanoliter-scale droplets, which are… read more here.
Keywords: based rna; probe; fnap sort; fret based ... See more keywords
Performance of a blood-based RNA signature for gemcitabine-based treatment in metastatic pancreatic adenocarcinoma
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Gastrointestinal Oncology"
DOI: 10.21037/jgo-22-946
Abstract: Background Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal cancer, and chemotherapy is a key treatment for advanced PDAC. Gemcitabine chemotherapy is still an important component of treatment; however, there is no routine biomarker to… read more here.
Keywords: based rna; blood based; blood; treatment ... See more keywords