Efficacy and Safety of a Protein-Based SARS-CoV-2 Vaccine
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2023.10302
Abstract: Key Points Question Do the protein-based SARS-CoV-2 vaccines (FINLAY-FR-2 and FINLAY-FR-1A) provide safe and effective protection against SARS-CoV-2? Findings In this randomized clinical trial including 23 959 individuals, vaccine efficacy for prevention of polymerase chain reaction… read more here.
Keywords: prevention; efficacy; sars cov; protein based ... See more keywords
NMR Based SARS-CoV-2 Antibody Screening
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.1c03945
Abstract: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) entry into cells is a complex process that involves (1) recognition of the host entry receptor, angiotensin-converting enzyme 2 (ACE2), by the SARS-CoV-2 spike protein receptor binding… read more here.
Keywords: antibody screening; based sars; spectroscopy; cov antibody ... See more keywords
Applying lessons learned from nanomedicines to understand rare hypersensitivity reactions to mRNA-based SARS-CoV-2 vaccines
Sign Up to like & getrecommendations! Published in 2022 at "Nature Nanotechnology"
DOI: 10.1038/s41565-022-01071-x
Abstract: After over a billion of vaccinations with messenger RNA-lipid nanoparticle (mRNA-LNP) based SARS-CoV-2 vaccines, anaphylaxis and other manifestations of hypersensitivity can be considered as very rare adverse events. Although current recommendations include avoiding a second… read more here.
Keywords: cov vaccines; mrna based; based sars; reactions mrna ... See more keywords
A PCR amplicon-based SARS-CoV-2 replicon for antiviral evaluation
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-82055-0
Abstract: The development of specific antiviral compounds to SARS-CoV-2 is an urgent task. One of the obstacles for the antiviral development is the requirement of biocontainment because infectious SARS-CoV-2 must be handled in a biosafety level-3… read more here.
Keywords: rna; based sars; antiviral evaluation; sars cov ... See more keywords
Implications of mRNA-based SARS-CoV-2 vaccination for cancer patients
Sign Up to like & getrecommendations! Published in 2021 at "Journal for Immunotherapy of Cancer"
DOI: 10.1136/jitc-2021-002932
Abstract: SARS-CoV-2 infection and the resulting COVID-19 have afflicted millions of people in an ongoing worldwide pandemic. Safe and effective vaccination is needed urgently to protect not only the general population but also vulnerable subjects such… read more here.
Keywords: mrna based; patients cancer; based sars; cancer ... See more keywords
Scalable RT‐LAMP‐based SARS‐CoV‐2 testing for infection surveillance with applications in pandemic preparedness
Sign Up to like & getrecommendations! Published in 2023 at "EMBO Reports"
DOI: 10.15252/embr.202357162
Abstract: Throughout the SARS‐CoV‐2 pandemic, limited diagnostic capacities prevented sentinel testing, demonstrating the need for novel testing infrastructures. Here, we describe the setup of a cost‐effective platform that can be employed in a high‐throughput manner, which… read more here.
Keywords: based sars; surveillance; sars cov; lamp based ... See more keywords
Short-term safety and immunogenicity of inactivated and peptide-based SARS-CoV-2 vaccines in patients with endocrine-related cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1028246
Abstract: Background The aim of this study was to explore the short-term safety and immunogenicity of inactivated and peptide-based SARS-CoV-2 vaccines in patients with endocrine-related cancer (ER). Methods Eighty-eight patients with ER cancer and 82 healthy… read more here.
Keywords: peptide based; based sars; cov vaccines; inactivated peptide ... See more keywords