Converging a Knowledge-Based Scoring Function: DrugScore2018
Sign Up to like & getrecommendations! Published in 2019 at "Journal of chemical information and modeling"
DOI: 10.1021/acs.jcim.8b00582
Abstract: We present DrugScore2018, a new version of the knowledge-based scoring function DrugScore, which builds upon the same formalism used to derive DrugScore but exploits a training data set of nearly 40 000 X-ray complex structures, a… read more here.
Keywords: knowledge based; based scoring; scoring function; drugscore2018 ... See more keywords
TRScore: a three-dimensional RepVGG-based scoring method for ranking protein docking models.
Sign Up to like & getrecommendations! Published in 2022 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btac120
Abstract: MOTIVATION Protein-protein interactions (PPI) play important roles in cellular activities. Due to the technical difficulty and high cost of experimental methods, there are considerable interests towards the development of computational approaches, such as protein docking,… read more here.
Keywords: protein protein; method ranking; protein docking; based scoring ... See more keywords
Symptom‐based scoring for haemorrhoidal disease: a systematic review
Sign Up to like & getrecommendations! Published in 2020 at "Colorectal Disease"
DOI: 10.1111/codi.15253
Abstract: Haemorrhoidal disease can severely affect a patient’s quality of life. Its classification is commonly based on morphology of the degree of prolapse; however, this does not take into account the symptoms and impact on the… read more here.
Keywords: based scoring; haemorrhoidal disease; systematic review; disease ... See more keywords
Comparative Study of Transcriptomics-Based Scoring Metrics for the Epithelial-Hybrid-Mesenchymal Spectrum
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2020.00220
Abstract: The Epithelial–mesenchymal transition (EMT) is a cellular process implicated in embryonic development, wound healing, and pathological conditions such as cancer metastasis and fibrosis. Cancer cells undergoing EMT exhibit enhanced aggressive behavior characterized by drug resistance,… read more here.
Keywords: based scoring; scoring metrics; emt status; comparative study ... See more keywords
Automatic BASED scoring on scalp EEG in children with infantile spasms using convolutional neural network
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.931688
Abstract: In recent years, the Burden of Amplitudes and Epileptiform Discharges (BASED) score has been used as a reliable, accurate, and feasible electroencephalogram (EEG) grading scale for infantile spasms. However, manual EEG annotation is, in general,… read more here.
Keywords: scoring scalp; convolutional neural; infantile spasms; automatic based ... See more keywords
Advanced multiparametric MRI-based scoring for isocitrate dehydrogenase mutation prediction of gliomas
Sign Up to like & getrecommendations! Published in 2022 at "Polish Journal of Radiology"
DOI: 10.5114/pjr.2022.121549
Abstract: Purpose To propose an advanced multiparametric magnetic resonance imaging (MRI)-based scoring system and evaluate its diagnostic accuracy with respect to the isocitrate dehydrogenase (IDH) mutation status of gliomas. Material and methods This prospective observational study… read more here.
Keywords: isocitrate dehydrogenase; glioma score; based scoring; advanced multiparametric ... See more keywords