siRNA‐based nanotherapeutics as emerging modalities for immune‐mediated diseases: A preliminary review
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DOI: 10.1002/cbin.11841
Abstract: Immune‐mediated diseases (IMDs) are chronic conditions that have an immune‐mediated etiology. Clinically, these diseases appear to be unrelated, but pathogenic pathways have been shown to connect them. While inflammation is a common occurrence in the… read more here.
Keywords: mediated diseases; review; based sirna; immune mediated ... See more keywords
Peptide-Based siRNA Nanocomplexes Targeting Hepatic Stellate Cells
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DOI: 10.3390/biom13030448
Abstract: Liver fibrosis is the excessive accumulation of extracellular matrix (ECM) in the liver due to chronic injuries and inflammation. These injuries activate and transform quiescent hepatic stellate cells (HSCs) into proliferative myofibroblast-like cells, which are… read more here.
Keywords: peptide based; stellate cells; activated hscs; liver ... See more keywords