Articles with "based sterically" as a keyword



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Delivery nanosystems based on sterically hindered phenol derivatives containing a quaternary ammonium moiety: Synthesis, cholinesterase inhibition and antioxidant activity.

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Published in 2019 at "Chemico-biological interactions"

DOI: 10.1016/j.cbi.2019.108753

Abstract: Multitarget ligands (MTL) based on sterically hindered phenol and containing a quaternary ammonium moiety (SHP-n-Q) were synthesized. These compounds are inhibitors of cholinesterases with antioxidant properties. The inhibitory selectivity is 10-fold potent for BChE than… read more here.

Keywords: sterically hindered; hindered phenol; containing quaternary; based sterically ... See more keywords