Biological macromolecules based targeted nanodrug delivery systems for the treatment of intracellular infections.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2018.01.030
Abstract: Intracellular infections are tricky to treat, the reason being the poor penetration of antibiotics/antimycotics into the microbial niche (host cell). Macrophages are primary targets of facultative and obligate intracellular bacteria/fungi to be abused as host… read more here.
Keywords: intracellular infections; macromolecules based; biological macromolecules; targeted nanodrug ... See more keywords
Fe–Al/AlSi compound casting based on a targeted oxide removal
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Materials Processing Technology"
DOI: 10.1016/j.jmatprotec.2017.05.004
Abstract: Abstract The compound casting technique is a promising approach to achieve a higher level of efficiency in technologically advanced components. This paper presents a compound material that is suitable for reinforcing an AlSi10Mg alloy. The… read more here.
Keywords: casting based; compound casting; alsi compound; compound ... See more keywords
LC-MS-Based Targeted Metabolomics for FACS-Purified Rare Cells
Sign Up to like & getrecommendations! Published in 2023 at "Analytical Chemistry"
DOI: 10.1021/acs.analchem.2c04396
Abstract: Metabolism plays a fundamental role in regulating cellular functions and fate decisions. Liquid chromatography-mass spectrometry (LC-MS)-based targeted metabolomic approaches provide high-resolution insights into the metabolic state of a cell. However, the typical sample size is… read more here.
Keywords: cell; targeted metabolomics; rare cell; metabolomics facs ... See more keywords
Application-Based Targeted Advertisement System for ATSC 3.0 UHD Service
Sign Up to like & getrecommendations! Published in 2021 at "IEEE Transactions on Broadcasting"
DOI: 10.1109/tbc.2020.3028337
Abstract: This study introduces a targeted advertisement service in the terrestrial UHD transmission environment by proposing a method to control advertisement exposure in real-time with minimal impact on current systems. The suggested system uses advertisement management… read more here.
Keywords: system; based targeted; real time; targeted advertisement ... See more keywords
Adaptive risk‐based targeted surveillance for foreign animal diseases at the wildlife‐livestock interface
Sign Up to like & getrecommendations! Published in 2022 at "Transboundary and Emerging Diseases"
DOI: 10.1111/tbed.14576
Abstract: Abstract Animal disease surveillance is an important component of the national veterinary infrastructure to protect animal agriculture and facilitates identification of foreign animal disease (FAD) introduction. Once introduced, pathogens shared among domestic and wild animals… read more here.
Keywords: surveillance; foreign animal; adaptive risk; risk based ... See more keywords
Application of Amplicon-Based Targeted NGS Technology for Diagnosis of Drug-Resistant Tuberculosis Using FFPE Specimens
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.01358-21
Abstract: Amplicon-based targeted NGS technology focuses on a set of gene mutations of known or suspected associations with drug susceptibility in Mycobacterium tuberculosis (MTB). This method offers many benefits, such as low sequencing cost, easy customization,… read more here.
Keywords: technology; amplicon based; targeted ngs; drug ... See more keywords
Padlock Probe-Based Targeted In Situ Sequencing: Overview of Methods and Applications.
Sign Up to like & getrecommendations! Published in 2023 at "Annual review of genomics and human genetics"
DOI: 10.1146/annurev-genom-102722-092013
Abstract: Elucidating spatiotemporal changes in gene expression has been an essential goal in studies of health, development, and disease. In the emerging field of spatially resolved transcriptomics, gene expression profiles are acquired with the tissue architecture… read more here.
Keywords: genetics; probe based; situ sequencing; padlock probe ... See more keywords
Performance evaluation of commercial library construction kits for PCR-based targeted sequencing using a unique molecular identifier
Sign Up to like & getrecommendations! Published in 2019 at "BMC Genomics"
DOI: 10.1186/s12864-019-5583-7
Abstract: BackgroundTarget enrichment is a critical component of targeted deep next-generation sequencing for the cost-effective and sensitive detection of mutations, which is predominantly performed by either hybrid selection or PCR. Despite the advantages of efficient enrichment,… read more here.
Keywords: construction; library construction; commercial library; construction kits ... See more keywords
Nano Architect-Based Targeted Delivery Systems for Diabetic Nephropathy: A Review.
Sign Up to like & getrecommendations! Published in 2023 at "Current drug targets"
DOI: 10.2174/1389450124666230601163338
Abstract: Diabetes mellitus is a long-lasting disease that is very common in the age group above 20 years and is characterized by hyperglycemia with other complications like Diabetic Nephropathy (DN). The management of DN focuses on… read more here.
Keywords: nano architect; based targeted; management; diabetic nephropathy ... See more keywords
Nanocarrier-Based Targeted Therapies for Myocardial Infarction
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14050930
Abstract: Myocardial infarction is a major cause of morbidity and mortality worldwide. Due to poor inherent regeneration of the adult mammalian myocardium and challenges with effective drug delivery, there has been little progress in regenerative therapies.… read more here.
Keywords: targeted therapies; nanocarrier based; myocardial infarction; infarction ... See more keywords
The Nanopore-Tweezing-Based, Targeted Detection of Nucleobases on Short Functionalized Peptide Nucleic Acid Sequences
Sign Up to like & getrecommendations! Published in 2021 at "Polymers"
DOI: 10.3390/polym13081210
Abstract: The implication of nanopores as versatile components in dedicated biosensors, nanoreactors, or miniaturized sequencers has considerably advanced single-molecule investigative science in a wide range of disciplines, ranging from molecular medicine and nanoscale chemistry to biophysics… read more here.
Keywords: tweezing based; functionalized peptide; detection; peptide nucleic ... See more keywords