The first AMPA receptor negative modulators based on the tetrahydroquinazoline scaffold
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DOI: 10.1016/j.mencom.2018.07.028
Abstract: A convenient approach to novel symmetric bispyrimidine diamines comprises SNAr reactions of 4-fluoropyrimidine N-oxide with alkane-α,ω-diamines with subsequent reduction of N-oxide function. The obtained substances were tested in patch-clamp experiments for the influence on the… read more here.
Keywords: negative modulators; modulators based; receptor negative; ampa receptor ... See more keywords