Telomerase‐based therapies in haematological malignancies
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3687
Abstract: Telomeres are specialized genetic structures present at the end of all eukaryotic linear chromosomes. They progressively get shortened after each cell division due to end replication problems. Telomere shortening (TS) and chromosomal instability cause apoptosis… read more here.
Keywords: cell; based therapies; haematological malignancies; therapies haematological ... See more keywords
Understanding embryonic development for cell‐based therapies of intervertebral disc degeneration: Toward an effort to treat disc degeneration subphenotypes
Sign Up to like & getrecommendations! Published in 2020 at "Developmental Dynamics"
DOI: 10.1002/dvdy.217
Abstract: Chronic low back and neck pain are associated with intervertebral disc degeneration and are major contributors to the global burden of disability. New evidence now suggests that disc degeneration comprises a spectrum of subphenotypes influenced… read more here.
Keywords: based therapies; degeneration; cell based; intervertebral disc ... See more keywords
Extra‐cardiac targets in the management of cardiometabolic disease: Device‐based therapies
Sign Up to like & getrecommendations! Published in 2021 at "ESC Heart Failure"
DOI: 10.1002/ehf2.13361
Abstract: Heart failure (HF) does not occur in a vacuum and is commonly defined and exacerbated by its co‐morbid conditions. Neurohormonal imbalance and systemic inflammation are some of the key pathomechanisms of HF but also commonly… read more here.
Keywords: cardiac targets; device based; based therapies; management ... See more keywords
Continuing Challenges in Advancing Preclinical Science in Skeletal Cell‐Based Therapies and Tissue Regeneration
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.3578
Abstract: Cell‐based therapies hold much promise for musculoskeletal medicine; however, this rapidly growing field faces a number of challenges. Few of these therapies have proven clinical benefit, and an insufficient regulatory environment has allowed for widespread… read more here.
Keywords: continuing challenges; science; based therapies; cell based ... See more keywords
A systematic review and meta‐analysis of observational studies of the association between the use of incretin‐based therapies and the risk of pancreatic cancer
Sign Up to like & getrecommendations! Published in 2022 at "Pharmacoepidemiology and Drug Safety"
DOI: 10.1002/pds.5550
Abstract: Some early reports in the medical literature have raised concern about a possible increased risk of pancreatic cancer associated with the use of two broad classes of incretin‐based therapies, dipeptidyl peptidase‐4 inhibitors, and glucagon‐like peptide‐1… read more here.
Keywords: incretin based; based therapies; pancreatic cancer; observational studies ... See more keywords
The role of ultrasound in enhancing mesenchymal stromal cell‐based therapies
Sign Up to like & getrecommendations! Published in 2020 at "Stem Cells Translational Medicine"
DOI: 10.1002/sctm.19-0391
Abstract: Mesenchymal stromal cells (MSCs) have been a popular platform for cell‐based therapy in regenerative medicine due to their propensity to home to damaged tissue and act as a repository of regenerative molecules that can promote… read more here.
Keywords: medicine; mesenchymal stromal; based therapies; cell based ... See more keywords
Academic cosmetic gynaecology and energy-based therapies: ambiguities, explorations, and FDA advisories
Sign Up to like & getrecommendations! Published in 2019 at "International Urogynecology Journal"
DOI: 10.1007/s00192-019-03959-0
Abstract: Reading this article [1], the passion and enthusiasm for further exploring the role of energy-based therapies in urogynaecology are palpable. New concept terminology such as Bacademic cosmetic gynaecology^ and Bpre-prolapse^ are introduced and questionable terms… read more here.
Keywords: based therapies; dysfunction; gynaecology; cosmetic gynaecology ... See more keywords
Vagus nerve stimulation as a tool for enhancing extinction in exposure-based therapies
Sign Up to like & getrecommendations! Published in 2018 at "Psychopharmacology"
DOI: 10.1007/s00213-018-4994-5
Abstract: RationaleEmotionally traumatic experiences can lead to maladaptive memories that are enduring and intrusive. The goal of exposure-based therapies is to extinguish conditioned fears through repeated, unreinforced exposures to reminders of traumatic events. The extinction of… read more here.
Keywords: based therapies; stimulation; exposure based; extinction ... See more keywords
The role of nonhuman primate models in the development of cell-based therapies for Parkinson’s disease
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neural Transmission"
DOI: 10.1007/s00702-017-1708-9
Abstract: Through the course of over three decades, nonhuman primate (NHP) studies on cell-based therapies (CBTs) for Parkinson’s disease (PD) have provided insight into the feasibility, safety and efficacy of the approach, methods of cell collection… read more here.
Keywords: based therapies; cell based; role; nonhuman primate ... See more keywords
Cell-based therapies for the treatment of myocardial infarction: lessons from cardiac regeneration and repair mechanisms in non-human vertebrates
Sign Up to like & getrecommendations! Published in 2018 at "Heart Failure Reviews"
DOI: 10.1007/s10741-018-9750-8
Abstract: Ischemic cardiomyopathy is the cardiovascular condition with the highest impact on the Western population. In mammals (humans included), prolonged ischemia in the ventricular walls causes the death of cardiomyocytes (myocardial infarction, MI). The loss of… read more here.
Keywords: heart; non human; based therapies; myocardial infarction ... See more keywords
Updates on Device-Based Therapies for Patients with Heart Failure
Sign Up to like & getrecommendations! Published in 2018 at "Current Heart Failure Reports"
DOI: 10.1007/s11897-018-0384-x
Abstract: Purpose of ReviewHeart failure is a growing epidemic. Optimal medical therapy remains the cornerstone of heart failure management but device-based therapies have been shown to contribute to morbidity and mortality reduction.Recent FindingsMultiple investigational trials had… read more here.
Keywords: device based; heart; based therapies; heart failure ... See more keywords