Nonplatinum‐based therapy with Paclitaxel and Capecitabine for advanced squamous cell carcinomas of the anal canal: A population‐based Danish anal cancer group study
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Medicine"
DOI: 10.1002/cam4.3886
Abstract: First‐line platinum‐based therapy for advanced squamous cell carcinomas of the anal canal (SCCA) implies a risk of substantial side effects, and data on second‐line treatment options are limited. Paclitaxel and Capecitabine are a well‐known regimen… read more here.
Keywords: squamous cell; carcinomas anal; anal canal; based therapy ... See more keywords
Outcomes in patients with newly diagnosed TP53‐mutated acute myeloid leukemia with or without venetoclax‐based therapy
Sign Up to like & getrecommendations! Published in 2021 at "Cancer"
DOI: 10.1002/cncr.33675
Abstract: Venetoclax (VEN) in combination with a hypomethylating agent (HMA) has become the standard of care for patients aged >75 years and for those not eligible for intensive chemotherapy who have newly diagnosed acute myeloid leukemia… read more here.
Keywords: patients newly; newly diagnosed; myeloid leukemia; acute myeloid ... See more keywords
A perspective on stem cell therapy for ear disorders
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26048
Abstract: The use of stem cells in cell‐based therapy is an emerging concept for the treatment of ear disorders. Tympanic membrane perforation (TMP) and inner ear disorders are some of the most commonly presented otologic disorders… read more here.
Keywords: ear disorders; cell based; therapy; stem ... See more keywords
Epigenetic‐based therapy for colorectal cancer: Prospect and involved mechanisms
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28658
Abstract: Epigenetic modifications are heritable variations in gene expression not encoded by the DNA sequence. According to reports, a large number of studies have been performed to characterize epigenetic modification during normal development and also in… read more here.
Keywords: colorectal cancer; crc; cancer; based therapy ... See more keywords
Recent Advances in Synthetic and Natural Biomaterials-Based Therapy for Bone Defects.
Sign Up to like & getrecommendations! Published in 2022 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202100383
Abstract: Synthetic and natural biomaterials are a promising alternative for the treatment of critical-sized bone defects. Several parameters such as their porosity, surface, and mechanical properties are extensively pointed out as key points to recapitulate the… read more here.
Keywords: synthetic natural; based therapy; natural biomaterials; bone ... See more keywords
Chemical modifications of nucleic acid drugs and their delivery systems for gene‐based therapy
Sign Up to like & getrecommendations! Published in 2018 at "Medicinal Research Reviews"
DOI: 10.1002/med.21479
Abstract: Gene‐based therapy is one of essential therapeutic strategies for precision medicine through targeting specific genes in specific cells of target tissues. However, there still exist many problems that need to be solved, such as safety,… read more here.
Keywords: delivery; acid drugs; gene based; based therapy ... See more keywords
The impact of a combined mentalisation-based therapy and therapeutic community programme for adolescents with borderline personality disorder traits on service utilisation in Western Australia.
Sign Up to like & getrecommendations! Published in 2023 at "Personality and mental health"
DOI: 10.1002/pmh.1579
Abstract: This study assessed the effect of a mentalisation-based therapy (MBT) treatment programme on the utilisation of Western Australian public hospitals for mental health presentations over an 18-month period. Hospital data included the number of visits… read more here.
Keywords: programme; based therapy; utilisation; community ... See more keywords
Outcome evaluation of a pharmacy‐based therapy management program for patients with cystic fibrosis
Sign Up to like & getrecommendations! Published in 2018 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.23978
Abstract: To compare medication adherence, pulmonary exacerbations, healthcare utilization, and costs for patients with cystic fibrosis (CF) who utilized a pharmacy‐based therapy management program to a matched control group. We hypothesized that patient management services would… read more here.
Keywords: cystic fibrosis; therapy management; management; patients cystic ... See more keywords
Functional Zeolitic Imidazolate Framework for Robust l-Deoxyribozyme-Based Therapy.
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DOI: 10.1002/smll.202204858
Abstract: Programmable chiral biocatalysis represents a promising therapeutic strategy for its high stereospecific control over various biotransformations (e.g., chiral Aβ isomerization) of living entities yet is rarely explored. With an extraordinary resistance to nuclease digestion, the… read more here.
Keywords: functional zeolitic; based therapy; imidazolate framework; therapy ... See more keywords
Amniotic membrane mesenchymal stem cells‐based therapy improves Bmi‐1‐deficient mandible osteoporosis through stimulating osteoblastic bone formation and inhibiting osteoclastic bone resorption
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.3300
Abstract: Mandible osteoporosis with age is characterized by greater fragility and accompanied with abnormal oral function. Mesenchymal stem cell transplantation can ameliorate osteoporosis. Bmi‐1 is a transcriptional repressor which is an important regulator of cell cycle,… read more here.
Keywords: mandible osteoporosis; bone; based therapy; bmi deficient ... See more keywords
Brown-Like Adipocyte Progenitors Derived from Human iPS Cells: A New Tool for Anti-obesity Drug Discovery and Cell-Based Therapy?
Sign Up to like & getrecommendations! Published in 2019 at "Handbook of experimental pharmacology"
DOI: 10.1007/164_2018_115
Abstract: Alternative strategies are urgently required to fight obesity and associated metabolic disorders including diabetes and cardiovascular diseases. Brown and brown-like adipocytes (BAs) store fat, but in contrast to white adipocytes, activated BAs are equipped to… read more here.
Keywords: brown like; anti obesity; tool; based therapy ... See more keywords