Tumor mutational burden quantification from targeted gene panels: major advancements and challenges
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DOI: 10.1186/s40425-019-0647-4
Abstract: Tumor mutational burden (TMB), the total number of somatic coding mutations in a tumor, is emerging as a promising biomarker for immunotherapy response in cancer patients. TMB can be quantitated by a number of NGS-based… read more here.
Keywords: quantification; based tmb; panel based; gene panels ... See more keywords