Design, synthesis, and structure–activity relationship of caffeine‐based triazoles as dual AChE and BACE‐1 inhibitors
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DOI: 10.1002/ddr.21998
Abstract: Natural products have significantly contributed to drug discovery for neurodegenerative diseases. Caffeine is one of the well‐known central nervous system(CNS)‐active natural products. Besides its CNS stimulant properties, it is a mild inhibitor of acetylcholinesterase (AChE)… read more here.
Keywords: bace; caffeine based; caffeine; ache ... See more keywords
Synthesis and Antibacterial Evaluation of Benzofuran Based Di-1,2,3-triazoles
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DOI: 10.1134/s1070363218070265
Abstract: A series of novel benzofuran-1,2,3-triazole hybrid molecules are synthesized using the click chemistry approach. Structures of the synthesized compounds were assessed by IR, NMR, and mass spectroscopy. The tests of final products 10a–10l for their… read more here.
Keywords: synthesis antibacterial; evaluation benzofuran; based triazoles; chemistry ... See more keywords