OpenEP: an open-source simulator for electroporation-based tumor treatments
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-020-79858-y
Abstract: Electroporation (EP), the increase of cell membrane permeability due to the application of electric pulses, is a universal phenomenon with a broad range of applications. In medicine, some of the foremost EP-based tumor treatments are… read more here.
Keywords: tumor treatments; based tumor; electroporated tissue; electroporation ... See more keywords
Nanomedicine-based tumor photothermal therapy synergized immunotherapy.
Sign Up to like & getrecommendations! Published in 2020 at "Biomaterials science"
DOI: 10.1039/d0bm01158d
Abstract: The emerging anti-tumor immunotherapy has made significant progress in clinical application. However, single immunotherapy is not effective for all anti-tumor treatments, owing to the low objective response rate and the risk of immune-related side effects.… read more here.
Keywords: based tumor; immunotherapy; therapy; photothermal therapy ... See more keywords
Hyaluronan Based Tumor-Targeting and pH-Responsive Shell Cross-Linkable Nanoparticles for the Controlled Release of Doxorubicin.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of biomedical nanotechnology"
DOI: 10.1166/jbn.2018.2510
Abstract: In this study, a series of amphiphilic polymeric prodrugs (Azido-functionalized hyaluronan-triazole-imine-doxorubicin, HAimine-DOX) were designed and synthesized by the "Click" reaction with a remarkable grafting ratio of DOX. Nanoparticles with a core-shell structure can be obtained… read more here.
Keywords: based tumor; doxorubicin; shell; hyaluronan based ... See more keywords
Prospective clinical evaluation of blood-based tumor mutational burden (bTMB) as a predictive biomarker for atezolizumab (atezo) in 1L non-small cell lung cancer (NSCLC): Interim B-F1RST results.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.12001
Abstract: 12001Background: TMB in both tissue and blood has shown promise in selecting for patients (pts) who clinically benefit from PD-L1/PD-1 inhibitors. In the randomized, 2L NSCLC Phase III OAK and Phas... read more here.
Keywords: based tumor; evaluation blood; clinical evaluation; blood ... See more keywords
The value of magnetic resonance imaging-based tumor shape features for assessing microsatellite instability status in endometrial cancer
Sign Up to like & getrecommendations! Published in 2022 at "Quantitative Imaging in Medicine and Surgery"
DOI: 10.21037/qims-22-77
Abstract: Background Microsatellite instability (MSI) status can be used for the classification and risk stratification of endometrial cancer (EC). This study aimed to investigate whether magnetic resonance imaging (MRI)-based tumor shape features can help assess MSI… read more here.
Keywords: msi status; shape features; status; based tumor ... See more keywords
Prognostic Value of CT Imaging-Based Tumor Volume in Patients With Non-Surgical Esophageal Squamous Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2020.602681
Abstract: Background The American Joint Committee on Cancer-Tumor (AJCC-T) staging system for esophageal carcinoma patients, which is based on the depth of tumor invasion, is not applicable in some cases. This study aims to assess the… read more here.
Keywords: based tumor; tumor volume; value; imaging based ... See more keywords
Maximum Somatic Allele Frequency-Adjusted Blood-Based Tumor Mutational Burden Predicts the Efficacy of Immune Checkpoint Inhibitors in Advanced Non-Small Cell Lung Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14225649
Abstract: Simple Summary Recent studies exhibited the unstable prediction ability of blood-based tumor mutational burden (bTMB) when predicting the response of immune checkpoint inhibitors (ICIs) therapy in patients with non-small cell lung cancer (NSCLC). Circulating tumor… read more here.
Keywords: tumor mutational; btmb; blood based; based tumor ... See more keywords
EPR Effect-Based Tumor Targeted Nanomedicine: A Promising Approach for Controlling Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm12010095
Abstract: Cancer remains the major threat to human health in most advanced countries in the world [...]. read more here.
Keywords: cancer; epr effect; tumor targeted; targeted nanomedicine ... See more keywords
Experimental study on the induction of cytotoxic T lymphocyte killing effects and dendritic-cell-based tumor vaccine prepared by high-intensity focused ultrasound
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cancer Research and Therapeutics"
DOI: 10.4103/jcrt.jcrt_2291_21
Abstract: Aims: This study was conducted to explore the high-intensity focused ultrasound (HIFU) prepared antigen-sensitized dendritic cells (DC) and the induction of cytotoxic T lymphocyte (CTL) killing effects by DC and to observe their anti-tumor immunity… read more here.
Keywords: vaccine prepared; cell; group; based tumor ... See more keywords