Optogenetic‐Controlled iPSC‐Based Vaccines for Prophylactic and Therapeutic Tumor Suppression in Mice
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202416115
Abstract: Induced pluripotent stem cells (iPSCs) share similar cellular features and various antigens profiles with cancer cells. Leveraging these characteristics, iPSCs hold great promise for developing wide‐spectrum vaccines against cancers. In practice, iPSCs are typically combined… read more here.
Keywords: ipsc based; controlled ipsc; optogenetic controlled; tumor ... See more keywords
Development of virus‐like particles‐based vaccines against coronaviruses
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology Progress"
DOI: 10.1002/btpr.3292
Abstract: Severe acute respiratory syndrome coronavirus (SARS‐CoV), Middle East respiratory syndrome coronavirus (MERS‐CoV), and the current severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) are the most impactful coronaviruses in human history, especially the latter, which brings… read more here.
Keywords: based vaccines; development; vaccines coronaviruses; virus like ... See more keywords
Carbohydrate‐based vaccines for oncotherapy
Sign Up to like & getrecommendations! Published in 2018 at "Medicinal Research Reviews"
DOI: 10.1002/med.21493
Abstract: Cancer is still one of the most serious threats to human worldwide. Aberrant patterns of glycosylation on the surface of cancer cells, which are correlated with various cancer development stages, can differentiate the abnormal tissues… read more here.
Keywords: cancer; vaccines oncotherapy; carbohydrate based; based vaccines ... See more keywords
Messenger RNA-Based Vaccines Against Infectious Diseases.
Sign Up to like & getrecommendations! Published in 2020 at "Current topics in microbiology and immunology"
DOI: 10.1007/82_2020_202
Abstract: In vitro-transcribed, messenger RNA-based infectious disease vaccines have the potential to successfully address many of the weaknesses of traditional vaccine platforms, such as the lack of potency and/or durability of vaccine protection, time-consuming, and expensive… read more here.
Keywords: based vaccines; infectious diseases; rna based; vaccine ... See more keywords
Rational Design of T Lymphocyte Epitope-Based Vaccines Against Coccidioides Infection.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7104-6_4
Abstract: Coccidioidomycosis is a potentially life-threatening mycosis endemic to the Southwestern USA and some arid regions of Central and South America. A vaccine against Coccidioides infection would benefit over 30-million people who reside in or visit… read more here.
Keywords: based vaccines; epitope based; coccidioides infection; vaccine ... See more keywords
Physiopathology and effectiveness of therapeutic vaccines against human papillomavirus
Sign Up to like & getrecommendations! Published in 2021 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-021-15441-w
Abstract: Human papillomavirus (HPV) is a well-known sexually transmitted disorder globally. Human papillomavirus (HPV) is the 3rd most common cancer that causes cervical carcinoma, and globally it accounts for 275,000 deaths every year. The load of… read more here.
Keywords: hpv associated; based vaccines; hpv; human papillomavirus ... See more keywords
Development of multi-epitope peptide-based vaccines against SARS-CoV-2
Sign Up to like & getrecommendations! Published in 2020 at "Biomedical Journal"
DOI: 10.1016/j.bj.2020.09.005
Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a pandemic involving so far more than 15 million infections and 630,211 deaths. Effective vaccines are urgently needed to prevent SARS-CoV-2 infections. No vaccines have yet… read more here.
Keywords: based vaccines; peptide based; epitope peptide; sars cov ... See more keywords
Methodological advances in the design of peptide-based vaccines.
Sign Up to like & getrecommendations! Published in 2022 at "Drug discovery today"
DOI: 10.1016/j.drudis.2022.03.004
Abstract: The tremendous advances in genomics, recombinant DNA technology, bioengineering and nanotechnology, in conjunction with the development of high-end computations, have been instrumental in the process of rational design of peptide-based vaccines. The use of peptide… read more here.
Keywords: based vaccines; design peptide; peptide based; methodological advances ... See more keywords
Post-adenoviral-based vaccines Guillain-Barre Syndrome: A proposed mechanism
Sign Up to like & getrecommendations! Published in 2022 at "Medical Hypotheses"
DOI: 10.1016/j.mehy.2022.110792
Abstract: Despite great public health advances achieved by COVID-19 vaccines, rare side effects may impact the public acceptance. Guillain-Barre Syndrome has increasingly been reported with adenoviral-based vaccines. This perspective proposes a possible mechanism underlying this rare… read more here.
Keywords: guillain barre; barre syndrome; based vaccines; adenoviral based ... See more keywords
Antibody-guided structure-based vaccines.
Sign Up to like & getrecommendations! Published in 2020 at "Seminars in immunology"
DOI: 10.1016/j.smim.2020.101428
Abstract: The vaccine field is pursuing diverse approaches to translate the molecular insights from analyses of effective antibodies and their targeted epitopes into immunogens capable of eliciting protective immune responses. Here we review current antibody-guided strategies… read more here.
Keywords: based vaccines; antibody guided; antibody; guided structure ... See more keywords
Medical and molecular biophysical techniques as substantial tools in the era of mRNA-based vaccine technology.
Sign Up to like & getrecommendations! Published in 2024 at "Biomaterials science"
DOI: 10.1039/d4bm00561a
Abstract: The COVID-19 pandemic prompted the advancement of vaccine technology using mRNA delivery into the host cells. Consequently, mRNA-based vaccines have emerged as a practical approach against SARS-CoV-2 owing to their inherent properties, such as cost-effectiveness,… read more here.
Keywords: mrna based; biophysical techniques; medical molecular; molecular biophysical ... See more keywords