Minicircle DNA: The Future for DNA-Based Vectors?
Sign Up to like & getrecommendations! Published in 2020 at "Trends in biotechnology"
DOI: 10.1016/j.tibtech.2020.04.008
Abstract: Minicircle DNA (mcDNA) is a smaller and safer version of non-viral DNA vectors that results from a cutting-edge in vivo recombination process to excise prokaryotic sequences from plasmid DNA (pDNA). Considering the molecule's potential and… read more here.
Keywords: minicircle dna; dna based; dna; based vectors ... See more keywords
Immunogenicity of ORFV-based vectors expressing the rabies virus glycoprotein in livestock species.
Sign Up to like & getrecommendations! Published in 2017 at "Virology"
DOI: 10.1016/j.virol.2017.08.027
Abstract: The parapoxvirus Orf virus (ORFV) encodes several immunomodulatory proteins (IMPs) that modulate host-innate and pro-inflammatory responses and has been proposed as a vaccine delivery vector for use in animal species. Here we describe the construction… read more here.
Keywords: rabies virus; immunogenicity; expressing rabies; immunogenicity orfv ... See more keywords
Bacteriophage-Mediated Cancer Gene Therapy
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232214245
Abstract: Bacteriophages have long been considered only as infectious agents that affect bacterial hosts. However, recent studies provide compelling evidence that these viruses are able to successfully interact with eukaryotic cells at the levels of the… read more here.
Keywords: therapy; gene therapy; cancer gene; cancer ... See more keywords