Baseline cell-free DNA (cfDNA) and metabolic tumor volume (MTV) independently predict outcome in metastatic chemorefractory colorectal cancer (mCRC).
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.11569
Abstract: 11569Background: No validated prognostic biomarker is currently available for mCRC. This trial assessed cfDNA and MTV before treatment with regorafenib as prognostic biomarkers for progression-free... read more here.
Keywords: dna cfdna; baseline cell; free dna; cfdna metabolic ... See more keywords
Haploinsufficiency of Insm1 Impairs Postnatal Baseline β-Cell Mass
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DOI: 10.2337/db17-1330
Abstract: Baseline β-cell mass is established during the early postnatal period when β-cells expand. In this study, we show that heterozygous ablation of Insm1 decreases baseline β-cell mass and subsequently impairs glucose tolerance. When exposed to… read more here.
Keywords: baseline cell; cell; cell mass; insm1 ... See more keywords