Incorporating baseline covariates to validate surrogate endpoints with a constant biomarker under control arm.
Sign Up to like & getrecommendations! Published in 2021 at "Statistics in medicine"
DOI: 10.1002/sim.9201
Abstract: A surrogate endpoint S in a clinical trial is an outcome that may be measured earlier or more easily than the true outcome of interest T. In this work, we extend causal inference approaches to… read more here.
Keywords: validate surrogate; potential outcomes; surrogate; incorporating baseline ... See more keywords
Abstract 3228: An online tool to balance baseline covariates for mouse clinical trials
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Research"
DOI: 10.1158/1538-7445.am2020-3228
Abstract: INTRODUCTION: Randomization is a cornerstone of controlled studies such as mouse clinical trials (MCT). However, simple randomization schemes often lead to unbalanced group allocations, therefore reducing the statistical power of experimental studies. This issue becomes… read more here.
Keywords: mouse clinical; online tool; clinical trials; baseline ... See more keywords